Review

Pregnancy associated cancer: General principles

Ioannis Rellias1, Alexandra Tsigginou1, Flora Zagouri2, Spyridon Marinopoulos1, Aris Giannos1, Kalliopi Pappa1, Constantine Dimitrakakis1

11st Department of Obstetrics and Gynecology, National & Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece
2Department of Therapeutics, National & Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece

Correspondence: Rellias I. 1st Department of Obstetrics and Gynecology, National & Kapodistrian University of Athens, Alexandra Hospital, Athens, 80 Vasilissis Sofias ave., PC 11528, Athens, Greece, Tel: +306947724381, E-mail: giannisrellias@gmail.com


Abstract

Pregnancy associated cancer is defined as the cancer diagnosed during pregnancy or within 1 year postpartum. Since women seem to be delaying childbearing to later ages than in previous generations, the incidence of cancer during pregnancy is constantly increasing. Treatment of cancer during pregnancy is a difficult clinical condition as both mother and fetus may be affected. This article summarizes the general principles in managing pregnant patient with cancer and notes some discrete problems in the management of specific cancers such as breast, cervical, ovarian cancer and melanoma. Of note, guidelines for the proper management of pregnant patient with cancer diagnosis are based on insufficient data from retrospective studies and case series. Hence, the management of these women should be individualized and performed in specialized centers with great experience and all cases should have multidisciplinary approach from multiple specialists such as medical oncologists, obstetricians, surgeons, radiologists and paediatricians.

Keywords: cancer, pregnancy, malignancy

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