Prediction of Gestational Diabetes Mellitus in the first trimester of pregnancy

Eleftheriades M, Karopoulou E, Papastefanou I, Kappou D, Sotiriadis A, Chrousos G

Gestational diabetes mellitus (GDM) is defined as any degree of carbohydrate intolerance with onset or first recognition during pregnancy. This entity has been increasing in prevalence and has been associated with various maternal and perinatal adverse outcomes. There is much controversy about the diagnostic criteria and management of GDM and current screening models are based on maternal and obstetric characteristics …


Diagnostic accuracy of the soluble Fms-like tyrosine kinase-1/placental growth factor ratio for preeclampsia with the use of a common cut-off value

Vasilios Pergialiotis, Anastasia Prodromidou, Alexandros Sotiriadis, Nikolaos Papantoniou

Background: To date, predictive markers of preeclampsia have not been established in the field of prenatal care. The Soluble fms-like tyrosine kinase-1/Platelet Growth Factor (sFlt-1/PlGF) ratio has been extensively studied in the literature and seems to be promising. However, consensus regarding its efficacy is lacking. Objective: The purpose of the present meta-analysis is to evaluate the …