Research
Maternal and perinatal outcomes in women with chronic hypertension and risk factors of superimposed preeclampsiaArife Simsek, Seyfettin Uludag, Abdullah Tuten, Sezin Uludag
Objective: The aim of this study is to evaluate obstetric outcomes among women with chronic hypertension, with and without superimposed preeclampsia, and identify risk factors of superimposed preeclampsia. Material and Methods: This retrospective study included 198 Caucasian women with chronic hypertension …
Review
The role of NK cells and HLA system in preeclampsiaKalinderis Michail, Kalinderi Kallirhoe, Papanikolaou Alexis
Preeclampsia is a pregnancy – specific syndrome associated with increased maternal and fetal morbidity and mortality. The development of preeclampsia occurs in two stages including reduced placental invasion, followed by the activation of endothelial cells and the release of various factors leading to the clinical manifestations of this syndrome. The initial trigger…
Meta-Analysis
Diagnostic accuracy of the soluble Fms-like tyrosine kinase-1/placental growth factor ratio for preeclampsia with the use of a common cut-off valueVasilios Pergialiotis, Anastasia Prodromidou, Alexandros Sotiriadis, Nikolaos Papantoniou
Background: To date, predictive markers of preeclampsia have not been established in the field of prenatal care. The Soluble fms-like tyrosine kinase-1/Platelet Growth Factor (sFlt-1/PlGF) ratio has been extensively studied in the literature and seems to be promising. However, consensus regarding its efficacy is lacking. Objective: The purpose of the present meta-analysis is to evaluate the …
Nikolakopoulos P
Humanin is a 24-amino acid peptide encoded by mitochondrial 16SRNA, that was firstly isolated from the occipital lobe of patients with Alzheimer’ s disease. Although it was identified as an antineuronal death factor, literature indicates humanin as a wide spectrum survival factor. To date, humanin has been shown to play a role in preventing cell death among various tissues outside …
Grammatikakis I, Evagelinakis N, Salamalekis G, Kassanos D
Pre-eclampsia, a pregnancy-specific disorder, contributes substantially to perinatal morbidity and mortality of both mother and newborn. An increasing number of biochemical agents has been evaluated as markers for predicting pre-eclampsia the last two decades, but none has been proved to be of clinical value yet. Much effort has been put into assessing novel potential markers …