Placental eicosanoids as endocrine and paracrine mediators during pregnancy

Iliodromiti Zoe, Grigoriadis Charalampos, Stournaras Stamatis, Daniilidis Angelos, Dafopoulos Konstantinos, Vrachnis Nikolaos

Eicosanoids, biologically active molecules possessing a wide range of functions, include prostaglandins, thromboxanes and leukotrienes. During pregnancy, eicosanoids are produced by the chorionic membranes and the decidua as well as by the placenta. The eicosanoids play an important role throughout pregnancy. During implantation, they enable the trophoblast to invade and colonize …

Case Report

Microscopic hematuria in the gynecologic and obstetric patient

Lazarou George, Stournaras Stamatios, Nousia Konstantina, Zygouris Dimitrios

Microscopic hematuria is a common finding in urinalysis during gynecological – obstetric control. We present the case of a 58 years old woman with recurrent hematuria in annual gynecological check. The literature review highlights a series of tests that must be carried out to investigate these cases. Medical history and physical examination are the first steps approach to identify …


Abnormal cytologic findings during pregnancy

Michail Georgios, Androutsopoulos Georgios, Georgantis Apostolos, Adonakis Georgios, Decavalas Georgios

Our aim was the illustration of the controversies that occur during pregnancy related to the mode of obtaining and interpreting a cervical smear, specific colposcopic features, as well as the approach of diagnosing, following- up and treatment, based on the findings of the Papanicolaou smear. A review of the literature as well as the updated American Society of Colposcopy …


Exposure to ionizing radiation and pregnancy

Kathopoulis Nikolaos, Moirogiorgos Dimitrios, Thomakos Nikolaos, Rodolakis Alexandros

The exposure of pregnant women to ionizing radiation is often a source of concern and provokes many questions. This anxiety is often unjustified and the questions are asked too late. Ignorance of the subject is likely to harm the woman who requires investigative imaging or lead to inappropriate attitudes to offer a medical termination of pregnancy after low-level exposure …

Case Report

Maternal Klippel – Trenaunay syndrome with complete hydatidiform mole and coexistent fetus: A case managed by surgical evacuation with review of literaturee

Ahmed Samy El-Agwany

Introduction: Klippel-Trenaunay Syndrome (KTS) is a rare triad of congenital vascular malformations involving extensive Port wine stains, soft tissue or bone hypertrophy and underlying venous and/or lymphatic malformation affecting limb, pelvic or abdominal organs. Pregnancies with a hydatidiform mole and a live fetus are extremely rare …


First trimester medical abortion: The several merits of combination mifepristone – misoprostol

Vrachnis Nikolaos, Zygouris Dimitrios, Lolos Markos, Dimitrakaki Alexandra, Salakos Nikolaos

Abortion is a very common procedure among women of reproductive age. Medical abortion is an alternative to surgical evacuation, especially in the early first trimester. Following the introduction of mifepristone, the number of medical abortions has rapidly increased. Mifepristone is used at doses of either 600mg or 200mg in combination with misoprostol and is regarded as a safe…


Burden of iron deficiency anemia in obstetrics

Angelos Daniilidis, Dimitrios Balaouras, Dimitrios Chitzios, Nikolaos Vrachnis, Christiana Zafeirati, Efstratios Asimakopoulos

Worldwide, attention over iron deficiency anemia (IDA) in pregnancy has been recently shifted towards supplementation during pregnancy and ensuring that women, especially adolescents have adequate iron stores prior to conception. Many researchers claim that adolescent or adult women still need supplements during pregnancy in order to avoid IDA, even if iron stores …

Asymptomatic bacteriuria and pregnancy

Thanasas I

Asymptomatic bacteriuria is common in pregnancy. History of urinary tract infection is the main predisposing factor and Escherichia coli is the most common pathogen. The diagnosis of asymptomatic bacteriuria is confirmed by the isolation of the causative bacteria in the culture of urine. The absence of clinical manifestations requires the implementation of urine culture to all pregnant …

Respiratory infections and pregnancy

Pitsiou G, Kioumis I

Respiratory infections during pregnancy, although not uncommon, do not represent a significant burden, however, their management requires special attention. Mostly important entities are pneumonia, influenza and tuberculosis. Diagnosis must be prompt and radiologic investigation can be safe, under the proper security measures. Therapeutic management needs to take in account not only …

Breast cancer and pregnancy: How, why, when

Daniilidis A, Hatzis P, Tantanasis T, Dinas K, Nasioutziki M, Carcea F, Giannoulis C, Loufopoulos A

The aim of the present review was to assess the relationship between pregnancy and breast cancer, the influence of pregnancy on mortality and prognosis of the disease, the consequences of breast cancer on pregnancy and to discuss the possible sequelae for the woman’s fertility. Pregnancy does not seem to influence the prognosis of an already established breast malignancy …