Editorial

Dimitris Loutradis

Gynecological cancers, including cervical, endometrial, ovarian, vaginal, and vulvar cancers, pose a significant threat to women’s health. The incidence of these malignancies has been reported to be on the rise, with an increase in the number of registered patients for all gynecological malignancies …

Posted in 2024 Volume 23 – Issue 1

Urological injuries following gynecologic surgery: clinical manifestations, diagnosis and management

Afroditi Ziogou, Alexios Giannakodimos, Ilias Giannakodimos, Aggelos Manikas, Eleftherios Ziogos

Iatrogenic urinary tract injury constitutes a rare but serious complication of gynecologic surgery, occurring in 0.3% to 1.5% of all procedures. Delayed diagnosis and repair are associated with increased postoperative morbidity, mortality and a long-term negative impact on the quality of life. Intraoperative detection of urinary tract injuries allows for prompt repair, facilitates management …

Posted in 2024 Volume 23 – Issue 1 Tagged , ,

Various interventions for infertility in men with type II diabetes and hypogonadism

Dimitra Gourma, Emmanouil Kalampokas, Olga Triantafyllidou, Theodoros Kalampokas, Nikolaos Vlachos

Background: Low levels of testosterone and sexual desire loss are common characteristics of hypogonadism, which is an endocrine disorder often occurring in men. Sexual dysfunction is an uncomfortable condition that both hypogonadal and diabetic men experience nowadays, however the diagnosis and treatment strategies are limited. Type II diabetes is a lifelong disorder …

Posted in 2024 Volume 23 – Issue 1 Tagged , , , ,

Thyroid disorders; an insidious cause leading to female infertility

Anastasios Potiris, Nikolaos Machairiotis, Ioannis Christidis, Theodoros Karampitsakos, Rita Variawa, Eirini Drakaki, Despoina Mavrogianni, Periklis Panagopoulos, Ekaterini Domali, Peter Drakakis, Sofoklis Stavros

The review aims to describe the effect of thyroid diseases on fertility. There are many causes of infertility in couples and thyroid dysfunction is a critical cause. Thyroid hormones and the hypothalamic-pituitary-ovarian axis interact in several ways and thyroid hormones may modulate ovarian functions. Hypothyroidism causes ovulatory dysfunction …

Posted in 2024 Volume 23 – Issue 1 Tagged , , , , ,

Comparative study of pluripotency-related gene expression in Umbilical Cord Mesenchymal Stem Cells (UC-MSC) from IUGR, SGA and normally grown fetuses

Panagiotis Fotinopoulos, Sotirios P Fortis, Louiza G Mahaira, Maria Salagianni, Vasilios Pergialiotis, Georgios Daskalakis, Nikolaos Papantoniou, Aris Antsaklis, Kalliopi I Pappa

Background and Objectives: Intrauterine growth restriction (IUGR) is worldwide a public health problem. IUGR-born individuals acquire epigenetic “thrifty-phenotype” gene adaptations, according to the “Barker hypothesis” and are more susceptible to develop metabolic related diseases. Small for Gestational Age (SGA) fetuses consist of a transitional group between IUGR and normally grown fetuses …

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Hemostatic Effect of Intrauterine Instillation of Oxytocin in Hysteroscopic Myomectomy: A Randomized Double Blinded Control Trial

Ghaleb M. Mahmoud, Walid Hitler Ahmed Tantawy, Amir Hamdy Abd El-Hady Mahfouz, Ahmed Mohamed Mamdouh

Introduction: Progesterone and oestrogen can have an impact on benign smooth muscle tumours of the uterus called uterine myomas. The majority of fibroids don’t cause any symptoms and don’t need to be treated or investigated further. Fibroids originate in the smooth muscles of the uterus and move to an area of decreased resistance, where they can either stay …

Posted in 2024 Volume 23 – Issue 1 Tagged , , ,

Frontal Lobe Growth impairment in fetuses with congenital heart disease using Ultrasound parameters; A Comparative Cross-sectional study

Noha Abd El-Sattar Afify Sakna, Mohamed Hassan Nasr El Din, Mourad Moustafa Attia Mohamed, Ahmed Mohamed Zeinhom

Introduction and the Αim: 2D and 3D biometry measures can record the increased development of the fetal brain in the later part of gestation. The objective of this study is to determine whether or not the frontal brain regions of fetuses with congenital …

Posted in 2024 Volume 23 – Issue 1 Tagged , , ,

Temporal trends of semen quality among male partners of infertile Greek couples undergoing oocyte donation cycles: a retrospective study in a single IVF center

Konstantinos Ravanos, Kyriaki Mitta, Ioannis Tsakiridis, Eleni-Markella Chalkia-Prapa, Yannis Prapas, Nikolaos Prapas, Apostolos Athanasiadis, Themistoklis Dagklis

Introduction: Temporal global trends of sperm quality remain a matter of debate. It is widely believed that exposure to endocrine disruptors during fetal life can damage testicular function, cause testicular cancer and impair reproduction …

Posted in 2024 Volume 23 – Issue 1 Tagged , , ,

A Complex Case of Neuroendocrine Carcinoma of the Cervix

Vasilios Lygizos, Iakovos Tomadakis, Dimitrios-Efthimios Vlachos, Kalliroi Goula, Nikolaos Thomakos, Dimitrios Haidopoulos

This case report presents the clinical course of a 56-year-old woman admitted to the Emergency Department with a complex array of symptoms, including vaginal bleeding, muscular weakness, and severe back pain. Subsequent investigations led to the diagnosis of a highly malignant neoplasm, suspected to be microcellular carcinoma …

Posted in 2024 Volume 23 – Issue 1 Tagged , , , , ,

OCT-4 and DAZL expression in benign and malignant breast lesions: a prospective case control study

Georgios Plakas, Iordanis Navrozoglou, Minas Paschopoulos, Theodoros Stefos, Konstantinos Stefanidis

Purpose: The impact of cancer stem cells on breast cancer tumor biology has been poorly investigated during the last years. In the present study we sought to identify the expression of OCT-4 and DAZL, two prominent stem cell biomarkers, on malignant breast lesions …

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