Τhe role of genes in the polycystic ovary syndrome: Predisposition and mechanisms

Kouskouti C, Kousteni E, Christopoulos P, Deligeoroglou E

The polycystic ovary syndrome (PCOS), mainly characterized by clinical and/or biochemical hyperandrogenism, ovarian dysfunction and/or polycystic morphology and associated metabolic disorders, is the most common endocrine disorder in women of reproductive age. The observed aggregation of PCOS cases within the same families and the persuasion that the interaction between multiple genetic …

The sentinel lymph node procedure in gynecologic oncology: Review of the literature

Kalogiannidis I, Xiromeritis P, Prapas Y, Prapas N

Lymphadenectomy contributes to the optimal staging and treatment of patients with gynecologic cancer. However, the former approach is not without adverse outcomes. The aim of the sentinel lymph node (SLN) procedure, which is the first node involved by the tumor, is to detect the group of patients with positive SLN, who will benefit from the lymphadenectomy. On the other hand …

Pathogenetic mechanisms of vaginal yeast infections

Αvgoulea A, Lambrinoudaki I, Creatsa M, Kaligerou I, Botsis D

Vulvovaginal fungal infection is one of the most common infections of the genital tract. Candida albicans is the most important cause of the infection. The presence of candida albicans in the vaginal liquid is not necessarily a pathologic finding and should be examined in correlation with the presence of the classical symptoms which include pruritus, dysuria and dyspareunia …

PAI-1 activity and polymorphism 4G/5G in women with idiopathic recurrent miscarriage

Sotiriadis A, Stefos T, Pavlou M, Kolaitis N, Vartholomatos G, Dova L, Paraskevaidis E, Kalantaridou S

Plasminogen activator inhibitor (PAI) indirectly affects trophoblastic invasion, antagonising the promoting effect of urokinase-type plasminogen activator (uPA). Plasminogen activator inhibitor (PAI) levels and the distribution of PAI-1 gene 4G/5G polymorphism were examined in 46 women with ≥2 consecutive unexplained first trimester abortions and 34 matched controls …

Episiotomy and repair of obstetric perineal injuries: The Greek current practice

Gregoriades T, Athanasiou S, Zisou A, Sotiropoulou M, Antsaklis A

To assess current practices regarding episiotomy and the repair of obstetric perineal injuries among Greek obstetricians and gynecologists and to identify any relative training deficiencies, a questionnaire was sent to obstetricians and gynecologists practicing in the Athens area. 121 out of 130 questionnaires were completed. An episiotomy was always performed by 50% of the doctors …