Systemic lupus erythematosus and pregnancy

Grammatikakis J, Salamalekis G, Evagelinakis N, Patsouras K, Kassanos D

Women with systemic lupus erythematosus (SLE) face significant risks in pregnancy. Pregnancy in SLE should be planned and a management strategy should be agreed with the patient, prior to conception. Pregnancy increases the likelihood of a lupus flare. Unfortunately, it is not possible to predict when, or if, an individual patient will flare, although flare is more likely …

The hormonal and metabolic profile of asymptomatic women with polycystic ovaries

Papathanasiou T

A significant proportion of women with polycystic ovaries have regular menstrual pattern and no overt symptoms or signs of hyperandrogenism. These women are thought to be healthy, while the incidental ultrasound finding of polycystic ovaries is dismissed as a normal variant. Recent studies, however, challenge these traditional views. A minority of these women exhibit anovulation …

Oral erythromycin and preterm rupture of membranes in pregnancy

Giannoulis H, Tantanasis T, Daniilidis A, Dinas K, Tzafettas J

The aim of our study was to compare the outcome of oral erythromycin in 32 cases of preterm rupture of membranes with that of oral co-amoxiclav (amoxicillin trihydrate and clavulanic acid) used as treatment in 19 cases of preterm rupture of membranes. Mean gestational age did not differ between the two groups (30 weeks), ranging from 26 to 33 weeks. In both groups the same tocolytics …