Chatzopoulos K, Kourtis A, Tantsis A, Agorastos T
The etiopathogenesis of endometriosis is complex. During menstruation, endometrial cells reflux backwards to the peritoneal cavity. In cases of endometriosis these cells have reduced apoptotic response due to activation of oncogenes and deregulation of normal apoptotic mechanisms. By entering the peritoneal cavity, they contact an environment rich in estrogens and growth factors …