Determining strategy of the non-invasive prenatal screening for chromosomal defects

Xiromeritis PN, Tsapanos VS

The need to reduce the rate of invasive screening (chorionic villous sampling, amniocentesis), and to detect the high risk pregnancies for chromosomal anomalies as early as possible, led to the concept of the sequential non-invasive screening, based on the Bayes theorem. The numerous non-invasive screening tests for chromosomal defects, should provide the calculation …

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