Gonadotropin surge attenuating factor: Α physiological regulator

Messinis Ioannis, Messini Christina, Dimitraki Marina, Anifandis George, Dafopoulos Konstantinos

Gonadotropin surge attenuating factor (GnSAF) is a non- steroidal ovarian substance, which attenuates the endogenous LH surge in superovulated women. Although several attempts have been made to purify GnSAF from various biological materials, different sequences were found. Only one of them has shown substantial homology of GnSAF to a known portion of the human genome …


Initial steps and mechanisms of HPV infection

Androutsopoulos Georgios, Thanatsis Nikolaos, Michail Georgios, Adonakis Georgios, Decavalas Georgios

Human papillomaviruses (HPV) are small, non-enveloped viruses. They have circular double-stranded DNA in an icosahedral capsid. Structural proteins of viral capsid, play important role in efficient virus infectivity. The viral L1 protein binds to the exposed basement membrane via heparan sulphate proteoglycans (primary receptor) and α6 integrin (secondary receptor) …

Case Report

Adnexal torsion in a 7 – year – old girl; dilemma in diagnosis and treatment

Singh Kamal, Thakur Sita, Sharma Monika

Ovarian torsion is an infrequent diagnosis in the pediatric age group but can be catastrophic, especially if ovarian salvage is not possible. The clinical picture is nonspecific, and children cannot always articulate their symptoms, which often make the diagnosis a challenge. Because of its nonspecific manifestations, ovarian torsion is often confused with other conditions …

Case Report

Cervical Pregnancy: A case report

Christodoulaki Chrisi, Stratoudakis Georgios, Zygouris Dimitrios, Kastrinakis Konstantinos, Daskalakis Georgios, Panagopoulos Perikles

Cervical pregnancy is an extremely rare form of ectopic pregnancy. We present a case of a 30 years old patient, diagnosed with cervical pregnancy, in the 7th week of gestation. Initially pharmaceutical treatment was attempted, but due to severe vaginal bleeding the patient underwent surgical therapy. Early diagnosis and prompt treatment lead to a very good outcome minimizing …