Case Report

Ovarian cysts in pregnancy. When surgical treatment required and when monitoring preferred?

Kalmantis K, Petsa A, Alexopoulos E, Daskalakis G, Rodolakis A

Introduction: Ovarian cysts occur in 3% of pregnancies. Usually, they do not have clinical symptoms and are found accidentally during the ultrasound screening performed in the 1st trimester of pregnancy. Materials and Methods: Articles were identified through electronic databases; no date or language restrictions were placed; relevant citations were hand searched. The search was conducted using the following terms …


Surveillance of breast cancer patients following primary therapy

Rellias I, Marinopoulos S, Zagouri F, Dimitrakakis C

Objective: To offer a summary of evidence-based recommendations for the surveillance of breast cancer patients after primary treatment. Quality of evidence: A literature search was conducted in Pubmed/MEDLINE using the terms: breast cancer, follow-up, surveillance, survivorship, guidelines and survivorship care plans, with focus on review of recent guidelines published by major cancer organizations…


Assisted Reproduction Techniques; What’s old and what’s new

Panagakis G, Asimakopoulos G, Sfakianakis A, Theofanakis Ch, Kallianidis K, Drakakis P

The greatest achievement of assisted reproductive medicine was the birth of Louise Brown in 1978. It was the result of many efforts by Edwards & Steptoe to achieve pregnancy with in vitro fertilization (IVF). Since then, there has been a rapid development of assisted reproduction techniques, with the ultimate aim of making infertility treatment more effective and affordable for most couples. The thorough study …

Case Report

First live birth in Greece after blastocyst trophectoderm biopsy and preimplantation genetic diagnosis by karyomapping

Economou A.K , Wells D, Christopikou D, Tsorva E, Davies S, Mastrominas M

Preimplantation genetic diagnosis for single gene defects is a well established tool in assisted reproduction. Karyomapping is a genome-wide parental haplotyping technology using a high density single nucleotide polymorphism array that allows the diagnosis of any single gene defects and the majority of aneuploidies from the same embryonic sample post embryo biopsy. A couple, carriers of different cystic fibrosis (CF) mutations …


Preimplantation Genetic Diagnosis

Loutradis Dimitris

A benefit of the state-of-the-art in assistant reproductive treatment requires among others, a definitive preimplantation genetic diagnosis (PGD) as an alternative to prenatal diagnosis, for couples with a family history of a genetic disease. In the past, parents had to take the risk for an inherited genetic disorder, or undergo prenatal diagnostic testing and pregnancy termination …