Gynecological Cancer Awareness Month

Loutradis Dimitris

September is the Gynecological Cancer Awareness month. International societies estimate that approximately 600,000 women will be diagnosed worldwide with gynecological cancer this year and approximately 240,000 women will, ultimately, succumb to the disease …


Perioperative fluid management-Goal Directed Therapy (GDT)

Emmanouil Stamatakis, Guram Devadze, Sofia Hadzilia, Dimitrios Valsamidis

Perioperative goal-directed hemodynamic therapy is a protocolized treatment strategy aimed at optimization of global cardiovascular dynamics, including oxygen delivery to tissues and organ perfusion pressure. This is achieved by titrating fluids, vasopressors, and inotropes to predefined physiological target values of hemodynamic variables …


Breast implant – Associated Anaplastic large cell lymphoma

Charilaos Ioannidis

Breast Implant –Associated Anaplastic Large Cell Lymphoma is a newly recognized malignant neoplasm presenting in breasts of women who have had breast implants for cosmetic or reconstructive purposes. A review of the literature showed thatit is an uncommon, slow growing T-cell lymphoma with morphology and immunophenotype similar to anaplastic lymphoma kinase (ALK)-negative anaplastic large cell lymphoma …

Mini Review

Deep vein thrombosis in pregnancy

Zacharias Fasoulakis, Aikaterini Mpairami, George Asimakopoulos, Konstantinos Tasias, Michael Sindos, George Daskalakis, Alexandros Rodolakis, Marianna Theodora

Venous thrombotic events (VTE) prevalence is estimated to be 1-2 for every 10,000 pregnancies, making it one of main causes of maternal mortality in developed countries. VTE’s leading risk factors are history of the condition and hereditary thrombophilia. D-dimer tests conducted during pregnancies have in many cases led to false positive results while a few false negatives have also been found. For pregnant women …

Research Article

Relationship of soluble Fms-like tyrosine kinase 1, soluble endoglin, placental growth factor blood levels with the severity of late onset preeclampsia

Ethem Serdar Yalvac, Mustafa Kara, Emre Baser, Taylan Onat, Melike Demir Caltekin, Müjgan Ercan, Demet Aydogan Kirmizi

Purpose: Preeclampsia (PE) is a pregnancy-specific syndrome characterized by placentation disorder that increases maternal and fetal morbidity and mortality. Overproduction of anti-angiogenic factors such as soluble fms-like tyrosine kinase receptor 1 (sFlt-1) and soluble endoglin (sEng) and low production of placental growth factor (Pgf) from angiogenic factors contribute to preeclampsia pathogenesis …

Case Report

Toxoplasmosis, a rare case report that led to a successful pregnancy

Thomas Ntounis, Sofoklis Stavros, Antonios Koutras, Alexandros Katrachouras, Dimitrios Lentzaris, Aikaterini Domali, Kyriacos Konis, Peter Drakakis

A 19-year-old female patient was presented to our clinic for a pregnancy follow-up during which primary toxoplasmosis infection was diagnosed. The patient was successfully treated with spiramycin and finally delivered normally a healthy boy, on term. Serological tests (ELISA) for detection of anti-toxoplasma antibodies along with ultrasonography findings on the fetus are the gold standard for the diagnosis …

Letter to the Editor

The pandemic paradox: Delay in the treatment of a woman with endometrial cancer during COVID-19 outbreak

Konstantinos Zacharis, Polyxeni Vanakara, Alexandros Daponte

The novel coronavirus (COVID-19) outbreak has been declared a global pandemic. The containment measures implemented in recent weeks to tackle it have led in drastic alterations in people’s daily life. These changes were essential to reduce virus transmission and protect health systems1. However, lockdown and strict measures, including home quarantine and social distancing, have delayed the diagnosis or postponed the therapeutic management of patients with neoplasia, such as surgery…