Androutsopoulos Georgios, Michail Georgios, Adonakis Georgios, Decavalas Georgios
The epidermal growth factor system (EGF system) is present in human organs and play important role in cell proliferation, differentiation and apoptosis during embryogenesis and postnatal development. It has 4 receptors (EGFR, ErbB – 2, ErbB – 3 and ErbB – 4) and numerous ligands. Dysregulation of the epidermal growth factor system signaling network, is implicated in the pathogenesis of various disorders …