D. Karoutsos, Z. Fasoulakis, S. Michala, K. Stefanidis, P. Antsaklis
Glycosylated Fibronectin (GFN), a glycoprotein involved in cell adhesion and migration, has been implicated in several physiological and pathological processes. Current literature suggests its altered glycosylation patterns might be associated with various pregnancy complications with recent studies providing new empirical evidence from a cohort study …
George Asimakopoulos, Panagiotis Antsaklis, Mariana Theodora, Michael Sindos, Alexandros Rodolakis, Dimitrios Loutradis, George Daskalakis
Gestational diabetes mellitus (GDM) is defined as impaired glucose tolerance with onset or first recognition during pregnancy, which is characterized by increased insulin resistance. GDM affects about 10% of pregnancies and its prevalence is rising worldwide mainly due to the advancing maternal age and the increased prevalence of obesity. GDM is associated with pregnancy-related maternal and fetal morbidity (both antenatal and perinatal). Traditional treatments for the GDM include diet and, if it is necessary, insulin …
Argirios Rountis, Kalliopi Pappa
Gestational diabetes mellitus (GDM) typically occurs when maternal glucose metabolism fails to compensate for the gradually increasing insulin resistance which mainly derives from the indigenous production of diabetogenic placental hormones during pregnancy. With its rising prevalence nowadays, GDM constitutes one of the most serious health problems in pregnant women that may result in both maternal and neonatal adverse outcomes…
Anastasios Pandraklakis, Kalliopi Pappa
Diabetes mellitus(DM) in pregnancy is associated with an increased risk of fetal, neonatal, and offspring complications, as well as with long term complications in adulthood. DM may be pregestational (ie, type 1 or 2 diabetes diagnosed before pregnancy with a prevalence 1.8%) or gestational (ie, diabetes diagnosed during pregnancy with a prevalence 7.5%). The outcome mainly is related to the onset and duration of glucose intolerance during pregnancy and the severity of DM …