Thyroid disorders; an insidious cause leading to female infertility

Anastasios Potiris, Nikolaos Machairiotis, Ioannis Christidis, Theodoros Karampitsakos, Rita Variawa, Eirini Drakaki, Despoina Mavrogianni, Periklis Panagopoulos, Ekaterini Domali, Peter Drakakis, Sofoklis Stavros

The review aims to describe the effect of thyroid diseases on fertility. There are many causes of infertility in couples and thyroid dysfunction is a critical cause. Thyroid hormones and the hypothalamic-pituitary-ovarian axis interact in several ways and thyroid hormones may modulate ovarian functions. Hypothyroidism causes ovulatory dysfunction …

Temporal trends of semen quality among male partners of infertile Greek couples undergoing oocyte donation cycles: a retrospective study in a single IVF center

Konstantinos Ravanos, Kyriaki Mitta, Ioannis Tsakiridis, Eleni-Markella Chalkia-Prapa, Yannis Prapas, Nikolaos Prapas, Apostolos Athanasiadis, Themistoklis Dagklis

Introduction: Temporal global trends of sperm quality remain a matter of debate. It is widely believed that exposure to endocrine disruptors during fetal life can damage testicular function, cause testicular cancer and impair reproduction …

Perinatal outcomes following assisted reproductive technology: A Review of the Literature

Konstantina Papadatou, Eleftherios Zachariou, Vasilios Pergialiotis, George Daskalakis

Nowadays, infertility affects approximately 8-12% of the population. Μultiple causative factors are leading to the failure of subfertile couples to achieve a normal pregnancy, as well as various types of assisted reproductive techniques that have developed globally in order to confront infertility. Over the past few years, especially after the birth of the world’s first baby to be conceived by In Vitro Fertilization (IVF) …

Antibiotic resistance profiles from isolated bacteria in outpatient infertility clinic in Greece

Karakalpakis D, Kostaras K, Asonitis K, Dimitriadi D, Pittaras T, Charvalos E, Daikos G, Mantzourani M, Pappa K

Aim: To investigate the prevalence of common aerobic gram positive and gram negative bacteria, Mycoplasma hominis, Ureaplasma urealyticum and Chlamydia trachomatis in symptomatic and asymptomatic Greek patients and to determine antibiotic resistance profiles. Methods: This retrospective study included a total of 316 adult men examined at the Assisted Reproduction Department …

Vaginal misoprostol (Prostin®) for intrauterine insemination: A meta – analysis of randomized trials

Pergialiotis Vasilios, Frountzas Maximos, Stefanidis Konstantinos, Prodromidou Anastasia, Perrea Despina, Vlachos D Georgios

Introduction: The seminal fluid contains prostaglandins which seem to be important during the fertilization process. However, these are cleaved during semen preparation for intrauterine insemination (IUI). The purpose of the present meta – analysis is to investigate if vaginal application of prostaglandin E (PGE) improves the pregnancy rates among women undergoing IUI.

A practical guide for managing young women with primary ovarian insufficiency

Drakakis Peter, Tzouma Christina, Dalkalitsis Alexander, Calis Karim, Kalantaridou Sophia

Primary ovarian insufficiency (POI) is a condition characterized by sex-steroid deficiency, amenorrhea, infertility, and elevated gonadotropins in women younger than 40 years of age. Most affected women produce estrogen intermittently and may ovulate despite the presence of high gonadotropin concentrations. POI is a heterogeneous disorder and may occur as a result …

Infertility: Psychoemotional impact, emotional adjustment to fertility treatment and cognitive behavioral therapy

Efthimiou K, Perdikari E

According to the British Human Fertilization and Embryology Authority, it is estimated that one in six couples will have to deal with some kind of infertility during lifetime, while World Health Organization considers infertility as one of the major problems of world public health. The present review focuses on the psychosocial impact of infertility, its cognitive meaning and the emotional …

Incidence of malignancy in patients treated for infertility with assisted reproduction techniques

Hudecek R, Ventruba P, Tsompos C, Racanska E, Vavrusova R, Sarmanova J, Novak J

We investigated the potential relation between assisted reproduction technology (ART) and the risk of ovarian carcinoma (OC) by data analysis of our University-based clinical register and National Oncology Register of Czech republic (NOR). Analyzed data included 12,527 assisted reproduction treatment cycles performed at 4,360 patients within years 1982-2004. Among the 4,360 patients …