Mini Review

Deep vein thrombosis in pregnancy

Zacharias Fasoulakis, Aikaterini Mpairami, George Asimakopoulos, Konstantinos Tasias, Michael Sindos, George Daskalakis, Alexandros Rodolakis, Marianna Theodora

Venous thrombotic events (VTE) prevalence is estimated to be 1-2 for every 10,000 pregnancies, making it one of main causes of maternal mortality in developed countries. VTE’s leading risk factors are history of the condition and hereditary thrombophilia. D-dimer tests conducted during pregnancies have in many cases led to false positive results while a few false negatives have also been found. For pregnant women …


Fetal maternal immune cross talking and vaccination during pregnancy

Panagiota Masoura, Georgia Koutsogeorgopoulou, Diamanto Tsianni, Anastasia Kourtesa, Kalliopi Pappa

Maternal adaptations in pregnancy induce complex physiological changes of the immune system which protect mother’s health and ensure the accommodation of the growing embryo. The innate immunity is amplified and the adaptive immunity is partially suppressed, preserving the ability to produce antibodies…

Research Article

Physical activity and exercise during pregnancy in Greece: A cross-sectional study

Ermioni Tsarna, Ioanna Mavrommati, Grigorios Bogdanis, Olga Triantafillidou,  George Paltoglou, Panagiotis Christopoulos

Introduction: Physical activity and exercise during pregnancy is regarded safe and beneficial in absence of pregnancy complications. The aim of this cross-sectional study is to describe physical activity of pregnant women in Greece and explore if it changes during pregnancy compared to the period before pregnancy…

Research Article

Overweight in childhood and early adulthood is associated with parental Body Mass Index and perinatal risk factors

Konstantinos D. Tambalis, Demosthenes B. Panagiotakos, Labros S. Sidossis

Background: To investigate the associations of pregnancy and pre-pregnancy parental characteristics on child’s weight and progression at the early adulthood. Material and Methods: Α random sample of 5,125 dyads children and their mothers was assessed. Mothers were asked to provide information contained in their medical booklets and pregnancy ultrasound records. With the use of a standardized questionnaire, telephone interviews were carried out for the collection of parental factors and offspring’s BMI…

Case Report

Luteal phase pregnancy after mirena coil insertion for intrauterine septum resection

Natasha Louise Citeroni, Rifat Syed

This report is of an unusual case of an intrauterine singleton pregnancy with a Mirena Coil (IUS) in situ following an elective hysteroscopic intrauterine septum resection for treatment of primary subfertility in a 27-year-old female. The patient elected to continue with the pregnancy and underwent additional monitoring via ultrasound. A caesarean section was undertaken at 39-weeks gestation and a healthy male infant was born …

Research article

The Effect of music on maternal anxiety and maternal and fetal heart rate during cardiotocography

Milona Gabriella, Pergialiotis Vasilios, Theodora Marianna, Loutradis Dimitrios, Daskalakis Georgios



Introduction: It is well known that music acts as an analgesic. Facilitates muscle relaxation, reduction of physical pain and mental tension. Purpose of this original investigation: study the effect of music on maternal anxiety during cardiotocography as well as its effect on embryonic cardiac function in relation to mother’s heart rate. Method and materials: The survey, conducted in external midwifery medical services of Alexandra’s Hospital, involved 80 pregnant women who met the criteria for participation. They were divided in two groups…

Research article

Smoking during pregnancy was negatively associated with physical fitness in childhood

Konstantinos D. Tambalis, Stamatis Mourtakos, Demosthenes D. Panagiotakos, Labros S. Sidossis


Background: To explore the potential relationship of several prenatal predictors with physical fitness (PF) components among children. Material and Methods: Α random sample of 5,125 dyads children (8 to 9 years old) and their mothers was evaluated. Mothers were asked to provide information contained in their medical booklets and pregnancy ultrasound records. With the use of a standardized questionnaire, telephone interviews were carried out for the collection of maternal factors in order to assess the potential association between several prenatal factors…

Case Report

Prenatal diagnosis of a large suprasellar arachnoid cyst

George Asimakopoulos, Panagiotis Antsaklis, Mariana Theodora, Michael Sindos, Alexandros Rodolakis, Dimitrios Loutradis, George Daskalakis


Arachnoid cysts represent 1% of all intracranial lesions and appear on the arachnoid membrane (subarachnoid space). The etiology and pathogenesis of arachnoid cysts remain unclear and in their majority they are asymptomatic. Due to the developmental origin of arachnoid cysts, these formations can be identified on prenatal fetal imaging. In this report we presented a case of an enlarged suprasellar arachnoid cyst detected incidentally during a routine fetal sonographic examination at 33 weeks of gestation …

Original Article

Intrahepatic cholestasis of pregnancy (ICP)

Panagiotis Antsaklis, Antonios Koutras, Nikolaos Thomakos, Dimitrios Loutradis



The first chapter of the article presents the general evidence, the clinical manifestation, the pathogenesis and diagnosis of the intrahepatic cholestasis, together with the risks involved for the mother and the fetus. The second chapter presents the treatment goals and the pharmacologic treatment during pregnancy, the management during and after delivery, as well as the risk of recurrence and future goals …

Case Report

Pemphigus vulgaris in pregnancy. A rare case report

Ioannis Kokolakis, Fanis Makrigiannakis, Sabine Kruger, Konstantinos Krasagakis, Antonios Makrigiannakis



Pemphigus vulgaris (PV) is an autoimmune, bullous, mucocutaneous and potentially life-threatening disease. During pregnancy the occurrence of PV is exceedingly rare and its condition will become more complicated due to different mother’s hormone level and the effect of treatment on both mother and her fetus. PV may be associated with an adverse outcome, such as fetal growth restriction and preterm births. We report a case of a 33-year-old woman who was firstly diagnosed with PV during pregnancy…