Indication-based administration of low dose aspirin for the prevention of preeclampsia: A retrospective study in Northern Greece

Ioanna Vagioni, Kyriaki Mitta, Ioannis Tsakiridis, Themistoklis Dagklis, Apostolos Athanasiadis, Apostolos Mamopoulos

Preeclampsia is a multisystem progressive disorder characterized by vascular abnormalities and coagulation disorders. The administration of low-dose aspirin is recommended before 16 weeks to delay or even avoid the onset of preeclampsia, based on screening tests. This study aimed to investigate the targeted or non-targeted administration of low-dose aspirin in pregnancies, according to the indications for its administration …

Primary and secondary prevention of uterine cervical cancer: Up-To-Date Information, Guidelines, and the need for their application in Greece

Dimitra Mitsopoulou, Angeliki-Astero Papathanasiou, Emmanouil Kalampokas, Nikolaos Vlahos

Background/Aim: Human papilloma virus (HPV) and uterine cervical cancer (UCC) are causatively related. In Greece, evidence-based guidelines for primary and secondary prevention of UCC have yet to be developed and applied in clinical practice. Our purpose here is to present such guidelines together with up-to-date data on HPV screening protocols…

Prophylactic and therapeutic vaccines against HPV infection

Kontou S, Chaidogiannos K, Trianti M, Salamalekis E

Persistent infection with one of the oncogenic HPV types is necessary for the development of cervical cancer. The role of HPV in cervical carcinogenesis and their immune response have created expectations for prevention. Vaccines based on the induction of neutralizing antibodies against the HPV structural proteins L1 and L2 are termed “prophylactic”. Vaccines based on the induction …