{"id":457,"date":"2017-08-17T19:15:08","date_gmt":"2017-08-17T19:15:08","guid":{"rendered":"http:\/\/5.189.150.156\/~hjog\/?p=457"},"modified":"2017-09-12T18:22:00","modified_gmt":"2017-09-12T18:22:00","slug":"the-action-of-vegf-in-angiogenesis","status":"publish","type":"post","link":"https:\/\/hjog.org\/?p=457","title":{"rendered":"The action of VEGF in angiogenesis"},"content":{"rendered":"

Ralli C, Kontomanolis E., Liberis V<\/p>\n

Department of Obstetrics and Gynecology, Democritus University of Thrace, Alexandroupolis, Greece<\/p>\n

Correspondence:<\/em> Kontomanolis E, Department of Obstetrics and Gynecology, Democritus University of Thrace, GR-68100, Alexandroupolis, Greece. E-mail: mek-2@otenet.gr<\/p>\n

\"\"<\/a><\/p>\n

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Abstract<\/h5>\n

Angiogenesis is a complicated process where new blood vessels are being formed from already pre-existing vessels. For tumor growth and metastases to distant organs, angiogenesis is a biological prerequisite. Tumor cells produce angiogenic factors, including Vascular Endothelial Growth Factor( VEGF), basic Fibroblast Growth Factor (bFGF), Platelet-Derived Endothelial Cell Growth Factor (PD-ECGF), and Transforming Growth Factor beta (TGF-\u03b2). VEGF being the most important angiogenic factor, found in four isoforms (VEGF165, VEGF121, VEGF189, VEGF206) and connected to three receptors tyrosine kinase (VEGFR-1, VEGFR-2 and VEGFR-3). Neuropilins (NPRs) are detected in a specific receptor which conforms to VEGF-A.<\/p>\n

Keywords:<\/em> angiogenesis, angiogenic factors, tumor, VEGF<\/p>\n

p. 91-95<\/p>\n

\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Ralli C, Kontomanolis E., Liberis V<\/p>\n

\"\"<\/a><\/p>\n

Angiogenesis is a complicated process where new blood vessels are being formed from already pre-existing vessels. For tumor growth and metastases to distant organs, angiogenesis is a biological prerequisite. Tumor cells produce angiogenic factors, including Vascular Endothelial Growth Factor( VEGF), basic Fibroblast Growth Factor (bFGF), Platelet-Derived Endothelial Cell Growth Factor (PD-ECGF) …<\/p>\n

“> Read More…<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[54],"tags":[471,472,473,474],"class_list":["post-457","post","type-post","status-publish","format-standard","hentry","category-2012-volume-11-issue-3","tag-angiogenesis","tag-angiogenic-factors","tag-tumor","tag-vegf"],"_links":{"self":[{"href":"https:\/\/hjog.org\/index.php?rest_route=\/wp\/v2\/posts\/457","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hjog.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hjog.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hjog.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/hjog.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=457"}],"version-history":[{"count":3,"href":"https:\/\/hjog.org\/index.php?rest_route=\/wp\/v2\/posts\/457\/revisions"}],"predecessor-version":[{"id":1034,"href":"https:\/\/hjog.org\/index.php?rest_route=\/wp\/v2\/posts\/457\/revisions\/1034"}],"wp:attachment":[{"href":"https:\/\/hjog.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=457"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hjog.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=457"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hjog.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=457"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}