{"id":655,"date":"2017-09-04T20:21:56","date_gmt":"2017-09-04T20:21:56","guid":{"rendered":"http:\/\/5.189.150.156\/~hjog\/?p=655"},"modified":"2022-02-02T11:01:19","modified_gmt":"2022-02-02T11:01:19","slug":"reviewfertility-sparing-options-for-women-with-ovarian-neoplasm","status":"publish","type":"post","link":"https:\/\/hjog.org\/?p=655","title":{"rendered":"Fertility sparing options for women with ovarian neoplasms"},"content":{"rendered":"<p><span style=\"color: #ff9900;\">Review<\/span><\/p>\n<p>Zygouris Dimitrios<sup>1<\/sup>, Panagopoulos Perikles<sup>1<\/sup>, Christodoulaki Chrysi<sup>1<\/sup>, Vrachnis Nikolaos<sup>2<\/sup>, Georgiou Athanasios<sup>1<\/sup>, Chrelias Charalampos<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>3rd Department of Obstetrics and Gynecology, University of Athens, Medical School, Attiko hospital<br \/>\n<sup>2<\/sup>2nd Department of Obstetrics and Gynecology, University of Athens Medical School, Aretaieio hospital<\/p>\n<p><em>Correspondence:<\/em> Zygouris Dimitrios, Papazoglou16, Ioannina, GR &#8211; 45444, Greece, E &#8211; mail: dzygouris@hotmail.com<\/p>\n<p style=\"text-align: right;\"><a href=\"https:\/\/hjog.org\/wp-content\/pdf\/2014\/Fertility sparing options for women with ovarian neoplasms p45-52.pdf\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-130\" src=\"https:\/\/hjog.org\/wp-content\/uploads\/2017\/08\/pdf-icons-free-icons-in-file-icons-18.png\" alt=\"\" width=\"48\" height=\"48\" \/><\/a><\/p>\n<hr \/>\n<h5>Abstract<\/h5>\n<p>Ovarian cancer is the leading cause of death by gynecological cancer and it is estimated that up to 17% of cases occur in women less than 40 years. In these patients it is often vital to maintain their fertility. This can be achieved using either fertility sparing types of surgery under strict selection criteria, or in combination with methods of assisted reproduction. In any case this should be avoided in patients over 40 years, and patients should be fully aware of the potential oncology and reproductive outcome. It is also needed a comprehensive surgical staging and patient\u2019s acceptance of a very close postoperative follow up. For patients with borderline tumor fertility sparing surgery is a safe option, with high percentages of achieved pregnancies and can be used either ovarian stimulation or ovarian tissue cryopreservation. In cases of invasive epithelial ovarian cancer fertility sparing clearly raises more concerns. The fertility surgery is recommended for patients with stage IA and low risk factors and under strict conditions for stages IB and IC, but beyond it is not considered safe choice. After surgery, pregnancy can be achieved by natural conception or assisted reproduction. In recent years there is growing debate on in vitro maturation of oocytes and growth to maintain fertility, making it a promising alternative. Furthermore,<br \/>\ncryopreservation of ovarian tissue is discussed and has found application in several experimental studies, but without sufficient data.In conclusion, we should mention that many methods are at an early stage and clinicians should always personalize each patient\u2019s treatment and provide full information about the chances of disease recurrence and the percentages of getting pregnant.<\/p>\n<p><em>Keywords:<\/em> epithelial ovarian cancer, borderline ovarian tumor, fertility sparing, ovarian neoplasms<\/p>\n<p>p. 59-66<\/p>\n<p>&nbsp;<\/p>\n<hr \/>\n","protected":false},"excerpt":{"rendered":"<p>Zygouris Dimitrios, Panagopoulos Perikles, Christodoulaki Chrysi, Vrachnis Nikolaos, Georgiou Athanasios, Chrelias Charalampos<\/p>\n<p style=\"text-align: right;\"><a href=\"https:\/\/hjog.org\/wp-content\/pdf\/2014\/Fertility sparing options for women with ovarian neoplasms p45-52.pdf\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-130\" src=\"https:\/\/hjog.org\/wp-content\/uploads\/2017\/08\/pdf-icons-free-icons-in-file-icons-18.png\" alt=\"\" width=\"48\" height=\"48\" \/><\/a><\/p>\n<p>Ovarian cancer is the leading cause of death by gynecological cancer and it is estimated that up to 17% of cases occur in women less than 40 years. In these patients it is often vital to maintain their fertility. This can be achieved using either fertility sparing types of surgery under strict selection criteria, or in combination with methods of assisted reproduction. In any case this should be avoided &#8230;<\/p>\n<p><a href=\"<?php echo get_permalink(); ?>&#8220;> Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[61],"tags":[648,421,425,649],"class_list":["post-655","post","type-post","status-publish","format-standard","hentry","category-2014-volume-13-issue-2","tag-borderline-ovarian-tumor","tag-epithelial-ovarian-cancer","tag-fertility-sparing","tag-ovarian-neoplasms"],"_links":{"self":[{"href":"https:\/\/hjog.org\/index.php?rest_route=\/wp\/v2\/posts\/655","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hjog.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hjog.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hjog.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/hjog.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=655"}],"version-history":[{"count":6,"href":"https:\/\/hjog.org\/index.php?rest_route=\/wp\/v2\/posts\/655\/revisions"}],"predecessor-version":[{"id":2515,"href":"https:\/\/hjog.org\/index.php?rest_route=\/wp\/v2\/posts\/655\/revisions\/2515"}],"wp:attachment":[{"href":"https:\/\/hjog.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=655"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hjog.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=655"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hjog.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=655"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}