Prediction of Gestational Diabetes Mellitus in the first trimester of pregnancy

Eleftheriades M, Karopoulou E, Papastefanou I, Kappou D, Sotiriadis A, Chrousos G

Gestational diabetes mellitus (GDM) is defined as any degree of carbohydrate intolerance with onset or first recognition during pregnancy. This entity has been increasing in prevalence and has been associated with various maternal and perinatal adverse outcomes. There is much controversy about the diagnostic criteria and management of GDM and current screening models are based on maternal and obstetric characteristics …


Pregnancy associated cancer: General principles

Ioannis Rellias, Alexandra Tsigginou, Flora Zagouri, Spyridon Marinopoulos, Aris Giannos, Kalliopi Pappa, Constantine Dimitrakakis

Pregnancy associated cancer is defined as the cancer diagnosed during pregnancy or within 1 year postpartum. Since women seem to be delaying childbearing to later ages than in previous generations, the incidence of cancer during pregnancy is constantly increasing. Treatment of cancer during pregnancy is a difficult clinical …

Case Report

Melanoma metastatic to the breast

Ioannidis Charilaos

Metastatic tumors to the breast are rare. A case of a 49- year old female patient with a fast growing breast lump, that proved to be metastatic melanoma from an earlier treated cutaneous melanoma of the lower extremity, is presented. Treatment suggestions are made considering the dismal prognosis of these patients …


HIV infection in pregnancy: Analysis of twenty cases

Kasioni Spiridoula, Pappas Stefanos, Vlachadis Nikolaos, Valsamidi Irene, Stournaras Stamatis, Nousia Konstantina, Farmakides George

Introduction: Prevention of mother – to – child transmission of HIV is at the forefront of global HIV prevention activities. Administration of antiretroviral drugs to mothers and neonates, scheduled caesarian section and prohibition of breastfeeding considerably have been indicated to decrease HIV transmission to the offspring. Material and Methods: We retrospectively analyzed 20 cases of HIV positive …


Gestational diabetes: Its classification and optimal management

Vitoratos Nikolaos, Vrachnis Nikolaos, Vlahos Nikolaos, Peristeris Kostantinos, Iliodromiti Zoe, Creatsas George

The classification of diabetes mellitus includes diabetes mellitus type I, diabetes mellitus type II, gestational diabetes and other specific types. Unfortunately, the incidence diabetes mellitus in pregnancy, or gestational diabetes, today ranging between 4 and 7%, has been globally on the rise in recent years, particularly among women over 32 years old. According to the International Association …

Case Report

Uterine prolapse complicating pregnancy: A case report

Ammari Alexandros, Tsikouras Panagiotis, Dimitraki Marina, Liberis Anastasios, Kontomanolis Emmanuel, Galazios Georgios, Liberis Vasileios

Uterine prolapse concurrent with pregnancy is a rare event. Complications resulting from the prolapse of the uterus in pregnancy vary from minor cervical infection to spontaneous abortion, preterm labor and maternal and fetal death. We report a case of stage 3 uterine prolapse during pregnancy presented at our antenatal clinic. The patient had pre-existing uterine prolapse, was treated …


Placental eicosanoids as endocrine and paracrine mediators during pregnancy

Iliodromiti Zoe, Grigoriadis Charalampos, Stournaras Stamatis, Daniilidis Angelos, Dafopoulos Konstantinos, Vrachnis Nikolaos

Eicosanoids, biologically active molecules possessing a wide range of functions, include prostaglandins, thromboxanes and leukotrienes. During pregnancy, eicosanoids are produced by the chorionic membranes and the decidua as well as by the placenta. The eicosanoids play an important role throughout pregnancy. During implantation, they enable the trophoblast to invade and colonize …

Case Report

Microscopic hematuria in the gynecologic and obstetric patient

Lazarou George, Stournaras Stamatios, Nousia Konstantina, Zygouris Dimitrios

Microscopic hematuria is a common finding in urinalysis during gynecological – obstetric control. We present the case of a 58 years old woman with recurrent hematuria in annual gynecological check. The literature review highlights a series of tests that must be carried out to investigate these cases. Medical history and physical examination are the first steps approach to identify …


Abnormal cytologic findings during pregnancy

Michail Georgios, Androutsopoulos Georgios, Georgantis Apostolos, Adonakis Georgios, Decavalas Georgios

Our aim was the illustration of the controversies that occur during pregnancy related to the mode of obtaining and interpreting a cervical smear, specific colposcopic features, as well as the approach of diagnosing, following- up and treatment, based on the findings of the Papanicolaou smear. A review of the literature as well as the updated American Society of Colposcopy …


Exposure to ionizing radiation and pregnancy

Kathopoulis Nikolaos, Moirogiorgos Dimitrios, Thomakos Nikolaos, Rodolakis Alexandros

The exposure of pregnant women to ionizing radiation is often a source of concern and provokes many questions. This anxiety is often unjustified and the questions are asked too late. Ignorance of the subject is likely to harm the woman who requires investigative imaging or lead to inappropriate attitudes to offer a medical termination of pregnancy after low-level exposure …