Obesity in pregnancy and gestational diabetes

Olga Triantafyllou, Kalliopi Pappa


Obesity is widely regarded as a major global pandemic that has extensive complications. Obesity rates have increased dramatically which can significantly lead to both maternal and fetal health complications during pregnancy. Obese women are predisposed to pregnancy complications such as gestational diabetes mellitus (GDM). Both share common metabolic characteristics. Obesity and gestational diabetes are both related to serious problems during pregnancy, but also to long term maternal – fetal consequences…


Diabetic ketoacidosis in pregnancy

Christos Kalantzis, Kalliopi Pappa



Diabetic ketoacidosis in pregnancy is a rare but potential life-threatening condition for the mother and the fetus. Although predictably DKP is more common in patients with type 1 diabetes, it has been reported too in those with type 2 diabetes as well as gestational diabetes. Diabetic ketoacidosis usually occurs in the second and third trimesters because of insulin resistance. Prompt recognition and aggressive treatment …


Management of low and high grade squamous intraepithelial lesions during pregnancy

Panagakis G., Theofanakis H, Pappa K, Loutradis D.

Despite significant advances regarding screening and treatment of cervical dysplasia, cervical cancer in fertile age is becoming more and more common in the last two decades. Cervical cancer screening ideally detects preinvasive lesions that can be eradicated or early stage cervical cancer that can be successfully treated. Cervical cancer screening was previously limited to cervical cytology. However, during the past decade…

Case Report

Neurofibromatosis-1 and Pregnancy: Case report

Kalmantis K, Petsa A, Daskalakis G, Alexopoulos E, Korovesi E, Antsaklis P, Karagkiouzis T

Introduction: Neurofibromatosis type-1 (NF-1) is one of the most common genetic diseases following an autosomal dominant inheritance pattern. Maternal and fetal complications have been reported. Purpose: To present a very interesting and rare case report regarding neurofibromatosis – 1 (NF-1) in pregnancy and to create a complete review concerning this genetic disease …


Preserving Fertility For Breast Cancer Patients: where do we stand today?

Psarris A, Marinopoulos S, Kallianidis K, Loutradis D, Drakakis P

Introduction: Breast cancer is the most common malignancy in women of reproductive age. The advances in treatment have resulted in an increased survival rate. However, keeping in mind that most women have not completed their families, treatment-related infertility poses a serious concern. The purpose of this review is to analyse the current options for fertility preservation in young breast cancer patients …

Case Report

Ovarian cysts in pregnancy. When surgical treatment required and when monitoring preferred?

Kalmantis K, Petsa A, Alexopoulos E, Daskalakis G, Rodolakis A

Introduction: Ovarian cysts occur in 3% of pregnancies. Usually, they do not have clinical symptoms and are found accidentally during the ultrasound screening performed in the 1st trimester of pregnancy. Materials and Methods: Articles were identified through electronic databases; no date or language restrictions were placed; relevant citations were hand searched. The search was conducted using the following terms …


Prediction of Gestational Diabetes Mellitus in the first trimester of pregnancy

Eleftheriades M, Karopoulou E, Papastefanou I, Kappou D, Sotiriadis A, Chrousos G

Gestational diabetes mellitus (GDM) is defined as any degree of carbohydrate intolerance with onset or first recognition during pregnancy. This entity has been increasing in prevalence and has been associated with various maternal and perinatal adverse outcomes. There is much controversy about the diagnostic criteria and management of GDM and current screening models are based on maternal and obstetric characteristics …


Pregnancy associated cancer: General principles

Ioannis Rellias, Alexandra Tsigginou, Flora Zagouri, Spyridon Marinopoulos, Aris Giannos, Kalliopi Pappa, Constantine Dimitrakakis

Pregnancy associated cancer is defined as the cancer diagnosed during pregnancy or within 1 year postpartum. Since women seem to be delaying childbearing to later ages than in previous generations, the incidence of cancer during pregnancy is constantly increasing. Treatment of cancer during pregnancy is a difficult clinical …

Case Report

Melanoma metastatic to the breast

Ioannidis Charilaos

Metastatic tumors to the breast are rare. A case of a 49- year old female patient with a fast growing breast lump, that proved to be metastatic melanoma from an earlier treated cutaneous melanoma of the lower extremity, is presented. Treatment suggestions are made considering the dismal prognosis of these patients …


HIV infection in pregnancy: Analysis of twenty cases

Kasioni Spiridoula, Pappas Stefanos, Vlachadis Nikolaos, Valsamidi Irene, Stournaras Stamatis, Nousia Konstantina, Farmakides George

Introduction: Prevention of mother – to – child transmission of HIV is at the forefront of global HIV prevention activities. Administration of antiretroviral drugs to mothers and neonates, scheduled caesarian section and prohibition of breastfeeding considerably have been indicated to decrease HIV transmission to the offspring. Material and Methods: We retrospectively analyzed 20 cases of HIV positive …