Case Report

Pemphigusvulgaris in pregnancy. A rare case report

Ioannis Kokolakis, Fanis Makrigiannakis, Sabine Kruger, Konstantinos Krasagakis, Antonios Makrigiannakis



Pemphigus vulgaris (PV) is an autoimmune, bullous, mucocutaneous and potentially life-threatening disease. During pregnancy the occurrence of PV is exceedingly rare and its condition will become more complicated due to different mother’s hormone level and the effect of treatment on both mother and her fetus. PV may be associated with an adverse outcome, such as fetal growth restriction and preterm births. We report a case of a 33-year-old woman who was firstly diagnosed with PV during pregnancy…

Case Report

Adnexal torsion during pregnancy: A rare cause of acute abdomen

Konstantinos Zacharis, Stavros Kravvaritis, Theodoros Charitos, Eleni Chrysafopoulou, Anastasia Fouka


Ovarian torsion is caused by rotation of the ovary or adnexa with the vascular pedicle on its axis resulting in arterial and venous obstruction. Here we report a case of a pregnant woman presented to the emergency department in early second trimester with acute abdomen. History revealed the presence of an ovarian mass detected by ultrasonography 6 months before pregnancy. Sonographic examination showed right adnexal mass with abnormal Doppler velocimetry and thus immediate laparotomy was decided. Right salpingo-oophorectomy was performed and post-operative course of the patient was uneventful…


Complications and Management of Asymptomatic Patients with Measles Infection During Pregnancy

Zacharias N Fasoulakis, Georgios Galazios, Vasileios Liberis, Emmanuel N Kontomanolis


Measles virus is a member of the family Paramyxoviridae that causes an epidemic disease with worldwide distribution, with the main symptom of this systematic disease being a prodrome of fever and a pathognomonic enanthema (Koplik spots), followed by a maculopapular rash. The rash usually appears about 14 days after the patient’s exposure and even though vaccination has led the virus to be limited to preschool children and young adults, measles infection can cause severe and even fatal complications in adults, pregnant women and immunocomprised patients…


Obesity in pregnancy and gestational diabetes

Olga Triantafyllou, Kalliopi Pappa


Obesity is widely regarded as a major global pandemic that has extensive complications. Obesity rates have increased dramatically which can significantly lead to both maternal and fetal health complications during pregnancy. Obese women are predisposed to pregnancy complications such as gestational diabetes mellitus (GDM). Both share common metabolic characteristics. Obesity and gestational diabetes are both related to serious problems during pregnancy, but also to long term maternal – fetal consequences…


Diabetic ketoacidosis in pregnancy

Christos Kalantzis, Kalliopi Pappa



Diabetic ketoacidosis in pregnancy is a rare but potential life-threatening condition for the mother and the fetus. Although predictably DKP is more common in patients with type 1 diabetes, it has been reported too in those with type 2 diabetes as well as gestational diabetes. Diabetic ketoacidosis usually occurs in the second and third trimesters because of insulin resistance. Prompt recognition and aggressive treatment …


Management of low and high grade squamous intraepithelial lesions during pregnancy

Panagakis G., Theofanakis H, Pappa K, Loutradis D.

Despite significant advances regarding screening and treatment of cervical dysplasia, cervical cancer in fertile age is becoming more and more common in the last two decades. Cervical cancer screening ideally detects preinvasive lesions that can be eradicated or early stage cervical cancer that can be successfully treated. Cervical cancer screening was previously limited to cervical cytology. However, during the past decade…

Case Report

Neurofibromatosis-1 and Pregnancy: Case report

Kalmantis K, Petsa A, Daskalakis G, Alexopoulos E, Korovesi E, Antsaklis P, Karagkiouzis T

Introduction: Neurofibromatosis type-1 (NF-1) is one of the most common genetic diseases following an autosomal dominant inheritance pattern. Maternal and fetal complications have been reported. Purpose: To present a very interesting and rare case report regarding neurofibromatosis – 1 (NF-1) in pregnancy and to create a complete review concerning this genetic disease …


Preserving Fertility For Breast Cancer Patients: where do we stand today?

Psarris A, Marinopoulos S, Kallianidis K, Loutradis D, Drakakis P

Introduction: Breast cancer is the most common malignancy in women of reproductive age. The advances in treatment have resulted in an increased survival rate. However, keeping in mind that most women have not completed their families, treatment-related infertility poses a serious concern. The purpose of this review is to analyse the current options for fertility preservation in young breast cancer patients …

Case Report

Ovarian cysts in pregnancy. When surgical treatment required and when monitoring preferred?

Kalmantis K, Petsa A, Alexopoulos E, Daskalakis G, Rodolakis A

Introduction: Ovarian cysts occur in 3% of pregnancies. Usually, they do not have clinical symptoms and are found accidentally during the ultrasound screening performed in the 1st trimester of pregnancy. Materials and Methods: Articles were identified through electronic databases; no date or language restrictions were placed; relevant citations were hand searched. The search was conducted using the following terms …


Prediction of Gestational Diabetes Mellitus in the first trimester of pregnancy

Eleftheriades M, Karopoulou E, Papastefanou I, Kappou D, Sotiriadis A, Chrousos G

Gestational diabetes mellitus (GDM) is defined as any degree of carbohydrate intolerance with onset or first recognition during pregnancy. This entity has been increasing in prevalence and has been associated with various maternal and perinatal adverse outcomes. There is much controversy about the diagnostic criteria and management of GDM and current screening models are based on maternal and obstetric characteristics …