Editorial

Prenatal care in the new era: 2014 – 15 update on earlier and less invasive individualized risk assessment

Vrachnis Nikolaos, Galazios Georgios, Stefos Theodoros

Prenatal care is the most widely used preventive service in the western world due to the recognition of its fundamental role in improving pregnancy outcome. The preventive nature of antenatal care, inspired by the teachings of Hippocrates, was re – introduced by John William Ballantyne in Edinburgh at the end of the 19th century, who focused on congenital anomalies, and later, during the first three decades of the 1900s, …

Research

Vaginal birth after cesarean section in Greece and the contribution of the midwives

Nousia Konstantina, Michalopoulos George, Grigoriadis Charalampos, Stournaras Stamatis, Brezeanou Christina, Vrachnis Nikolaos, Farmakides George

Introduction: The aim of this study was to examine the success rate and safety of vaginal delivery after cesarean section, as well as the value of midwives’ contribution in these cases. Material and Methods: This was a retrospective clinical study, including women diagnosed with singleton uncomplicated pregnancies and history of one or more previous cesarean sections, who underwent trial of labor, supported by midwives …

Review

Molecular biology, expression and clinical significance of ErbB receptors in endometrial cancer

Androutsopoulos Georgios, Michail Georgios, Adonakis Georgios, Decavalas Georgios

The epidermal growth factor system (EGF system) is present in human organs and play important role in cell proliferation, differentiation and apoptosis during embryogenesis and postnatal development. It has 4 receptors (EGFR, ErbB – 2, ErbB – 3 and ErbB – 4) and numerous ligands. Dysregulation of the epidermal growth factor system signaling network, is implicated in the pathogenesis of various disorders …

Review

Non – invasive prenatal diagnosis and cell free DNA analysis

Kalinderi Kallirhoe, Fidani Liana

Prenatal diagnosis is a very important part in the obstetric care of a pregnant woman. The use of invasive methods of prenatal screening provides great accuracy in the prenatal diagnosis of genetic and chromosomal abnormalities of the fetus; however it carries a small risk of fetal miscarriage. For this reason, the development of non-invasive methods of prenatal diagnosis is an area of intense research …

Case Report

Malignant melanoma and pregnancy: A case report

Thanasas Ioannis

Malignant melanoma in pregnancy is rare but its incidence is rapidly increasing due to the growing trend for child – bearing in advanced age. A case of malignant melanoma diagnosed in the 25th gestational week and treated with local surgical resection is presented. The patient had an uneventful remaining pregnancy, delivered by cesarian section at 37 weeks and has been disease – free for 1 year postpartum …

Letter to the Editor

Dynamic spectral imaging colposcopy

Sofoudis Chrisostomos, Salakos Nikolaos

cervical cancer is the most common cause of death from gynecological cancer in developing countries, with a mortality rate ten times higher than that in developed countries. It represents the third most common cancer in women after breast and colorectal cancer, with 528,000 estimated cases in 2012, 84% of these in less developed countries …