Homocysteine, cardiovascular disease and hormone replacement therapy in post-menopausal women

Deligeoroglou Ε, Tsimaris P, Deliveliotou A

Homocysteine (Hcy) is a sulfated amino acid deriving from methionine. Hcy’s metabolism, as well as the association of Hcy with cardiovascular disease (CVD) are extensively illustrated in this review article. The precise mechanism by which Hcy is involved in the pathogenesis and establishment of CVD, which is the leading cause of morbidity and mortality in postmenopausal women …