Live birth after polar body biopsy and preimplantation genetic screening of aneuploidy by DNA-microarray comparative genomic hybridisation

Economou K, Christopikou D, Tsorva E, Handyside A, Cazlaris H, Davies S, Mastrominas M

Α patient with a history of recurrent IVF failures was subjected to preimplantation genetic screening of aneuploidies by DNA microarray comparative genomic hybridisation (a-CGH). Oocytes that had been screened and found chromosomally euploid after biopsy of the first and second polar bodies were used, thereby avoiding the use of donated oocytes. A twin clinical pregnancy was achieved …

Total or subtotal abdominal hysterectomy in benign gynecological conditions: How, why, when?

Daniilidis Α, Spathopoulou S., Dinas Κ, Τantanasis T, Κartsea F, Giannoulis C, Balaouras D, Foteinakis I,Μakris V, Loufopoulos Α

Total and subtotal abdominal hysterectomy for benign indications have been compared in randomized clinical trials and observational studies. The aim of this review was to compare total and subtotal hysterectomy concerning incontinence, cervical stump problems, operation time, postoperative complications, quality of life, and prolapse. Incontinence, prolapse and cervical stumps problems …

Fertility-sparing surgical options in patients with early cervical cancer: Radical vaginal or abdominal trachelectomy?

Pigis D, Thomakos N, Lourantou D, Rodolakis A, Antsaklis A

Radical trachelectomy has emerged over the last years as a reasonable fertility-sparing operation for selected patients with stage I cervical cancer. The aim of this review was to summarize the latest literature and outline patient selection criteria, operative and oncologic outcomes. The majority of studies on fertility-sparing procedures in early stage cervical cancer examined …

Epithelial ovarian cancer of low malignant potential in a 15 year old patient: A case report

Ravanos Κ, Kologiannidis I, Tsertanidou A, Flaris N, Agorastos T

Epithelial ovarian cancer is extremely rare in adolescence but must be included in the differential diagnosis of an ovarian mass. Most patients present with early stage tumors of low malignant potential and achieve favorable overall survival. Preservation of fertility is essential, therefore conservative treatment is recommended according to oncological guidelines …