Research Article

The clinical significance of cutaneous metastasis and paraneoplastic skin lesions in ovarian cancer. A rare but not minor manifestation

Machairiotis N, Thomakos N, Malakasis A, Rodolakis A

Ovarian cancer results in the formation and proliferation of abnormal cells that have the ability to proliferate faster than normal/typical ovarian cells and then spread to other parts of the body either in a local or in a systemic way. The areas to which the metastases of ovarian cancer can be located include the lining of the abdomen, lining of the bowel and bladder, lymph nodes, lungs, liver and in very rare cases the skin …

Adnexal masses complicating pregnancy

Thomakos N, Chantzi H, Rodolakis A, Antsaklis A

The management of adnexal masses during pregnancy may be challenging for the patient and the clinician. Adnexal masses may be detected during prenatal ultrasound, and although such masses are rarely malignant (1/10.000 to 1/50.000 pregnancies), the probability of borderline tumor or cancer should always be considered. The etiology of ovarian masses differs according to the patient age …

The sentinel lymph node procedure in gynecologic oncology: Review of the literature

Kalogiannidis I, Xiromeritis P, Prapas Y, Prapas N

Lymphadenectomy contributes to the optimal staging and treatment of patients with gynecologic cancer. However, the former approach is not without adverse outcomes. The aim of the sentinel lymph node (SLN) procedure, which is the first node involved by the tumor, is to detect the group of patients with positive SLN, who will benefit from the lymphadenectomy. On the other hand …

Endometriosis and ovarian cancer

Baliakas D, Deliveliotou E, Giotis C, Vlachos N

Endometriosis and ovarian cancer share many molecular, pathogenetic and predisposing factors. In a molecular basis endometriosis and estrogen-dependent neoplasms respond similarly to estrogen-induced growth signalling. They have common resistance to apoptotic processes, whereas genetic mutations in the presence of endometriosis are associated with certain types of ovarian cancer …

Incidence of malignancy in patients treated for infertility with assisted reproduction techniques

Hudecek R, Ventruba P, Tsompos C, Racanska E, Vavrusova R, Sarmanova J, Novak J

We investigated the potential relation between assisted reproduction technology (ART) and the risk of ovarian carcinoma (OC) by data analysis of our University-based clinical register and National Oncology Register of Czech republic (NOR). Analyzed data included 12,527 assisted reproduction treatment cycles performed at 4,360 patients within years 1982-2004. Among the 4,360 patients …

Total laparoscopic radical hysterectomy with para-aortic and pelvic lymphadenectomy for stage IIA squamous cell carcinoma of the cervix: A case report

Chilaris GH, Tsoumpis T, Alarkof E, Karkotis K, Daveta A

The role of laparoscopy in the management of abdominopelvic malignancies is constantly evolving. Recebt data from clinical trials demonstrate that laparoscopic surgical staging has equal efficacy (lymph node counts, disease free survival) compared to traditional open cases and can be safely performed in selected patients. We report a case of laparoscopic radical hysterectomy …