Review

Abnormal cytologic findings during pregnancy

Michail Georgios, Androutsopoulos Georgios, Georgantis Apostolos, Adonakis Georgios, Decavalas Georgios

Our aim was the illustration of the controversies that occur during pregnancy related to the mode of obtaining and interpreting a cervical smear, specific colposcopic features, as well as the approach of diagnosing, following- up and treatment, based on the findings of the Papanicolaou smear. A review of the literature as well as the updated American Society of Colposcopy …

Review

Why Radical Trachelectomy and not Radical Hysterectomy for the treatment of early stage cervical cancer?

Nikolaos Thomakos, Sofia-Paraskevi Trachana, Michalis Liontos, Aristotelis Bamias, Alexandros Rodolakis

Cervical cancer is one of the most popular and lethal gynecological cancers worldwide. The standard treatment for early stage cervical cancer is radical hysterectomy combined with bilateral pelvic lymph node assessment. The infertility and the serious complications follow the radical hysterectomy, has lead gynecologic-oncologists to revise radical surgical approaches …

Fertility-sparing surgical options in patients with early cervical cancer: Radical vaginal or abdominal trachelectomy?

Pigis D, Thomakos N, Lourantou D, Rodolakis A, Antsaklis A

Radical trachelectomy has emerged over the last years as a reasonable fertility-sparing operation for selected patients with stage I cervical cancer. The aim of this review was to summarize the latest literature and outline patient selection criteria, operative and oncologic outcomes. The majority of studies on fertility-sparing procedures in early stage cervical cancer examined …

The sentinel lymph node procedure in gynecologic oncology: Review of the literature

Kalogiannidis I, Xiromeritis P, Prapas Y, Prapas N

Lymphadenectomy contributes to the optimal staging and treatment of patients with gynecologic cancer. However, the former approach is not without adverse outcomes. The aim of the sentinel lymph node (SLN) procedure, which is the first node involved by the tumor, is to detect the group of patients with positive SLN, who will benefit from the lymphadenectomy. On the other hand …

Total laparoscopic radical hysterectomy with para-aortic and pelvic lymphadenectomy for stage IIA squamous cell carcinoma of the cervix: A case report

Chilaris GH, Tsoumpis T, Alarkof E, Karkotis K, Daveta A

The role of laparoscopy in the management of abdominopelvic malignancies is constantly evolving. Recebt data from clinical trials demonstrate that laparoscopic surgical staging has equal efficacy (lymph node counts, disease free survival) compared to traditional open cases and can be safely performed in selected patients. We report a case of laparoscopic radical hysterectomy …

Prophylactic and therapeutic vaccines against HPV infection

Kontou S, Chaidogiannos K, Trianti M, Salamalekis E

Persistent infection with one of the oncogenic HPV types is necessary for the development of cervical cancer. The role of HPV in cervical carcinogenesis and their immune response have created expectations for prevention. Vaccines based on the induction of neutralizing antibodies against the HPV structural proteins L1 and L2 are termed “prophylactic”. Vaccines based on the induction …