Research

Evaluation of the quality of life of postmenopausal women using an estradiol and drospirenone combined oral hormone replacement therapy

Galazios George, Kalamara Eleni, Galaziou Aspasia, Tsikouras Panagiotis, Liberis Vasileios, Kolios George

Introduction: The aim of this study was to estimate the beneficial effects of drospirenone/estradiol combination in postmenopausal women, concerning the improvement of quality of life. Materials and Methods: Sixty one women took part in a non-comparative follow – up study after consent. They were up to one year menopausal, presented climasteric symptoms, had intact uterus and no contraindications …

Review

A practical guide for managing young women with primary ovarian insufficiency

Drakakis Peter, Tzouma Christina, Dalkalitsis Alexander, Calis Karim, Kalantaridou Sophia

Primary ovarian insufficiency (POI) is a condition characterized by sex-steroid deficiency, amenorrhea, infertility, and elevated gonadotropins in women younger than 40 years of age. Most affected women produce estrogen intermittently and may ovulate despite the presence of high gonadotropin concentrations. POI is a heterogeneous disorder and may occur as a result …

Homocysteine, cardiovascular disease and hormone replacement therapy in post-menopausal women

Deligeoroglou Ε, Tsimaris P, Deliveliotou A

Homocysteine (Hcy) is a sulfated amino acid deriving from methionine. Hcy’s metabolism, as well as the association of Hcy with cardiovascular disease (CVD) are extensively illustrated in this review article. The precise mechanism by which Hcy is involved in the pathogenesis and establishment of CVD, which is the leading cause of morbidity and mortality in postmenopausal women …