Review

Non – invasive prenatal diagnosis and cell free DNA analysis

Kalinderi Kallirhoe, Fidani Liana

Department of Medical Biology and Genetics, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece

Correspondence: Fidani Liana, Department of Medical Biology and Genetics, Medical School, Aristotle University of Thessaloniki, GR 54124, Thessaloniki, Greece, E – mail: lfidani@med.auth.gr


Abstract

Prenatal diagnosis is a very important part in the obstetric care of a pregnant woman. The use of invasive methods of prenatal screening provides great accuracy in the prenatal diagnosis of genetic and chromosomal abnormalities of the fetus; however it carries a small risk of fetal miscarriage. For this reason, the development of non-invasive methods of prenatal diagnosis is an area of intense research in which recently great progress has been made.

Keywords: prenatal diagnosis; cell free DNA

p. 84-90