Medications in pregnancy: challenges and concerns

Vrachnis Nikolaos, Loufopoulos Aristotelis

Pregnancy is a physiological condition in which drug treatment is a particularly delicate issue, since many medications can cross the blood – placental barrier and potentially cause harm to the fetus. In addition, the physiological changes in pregnancy can negatively affect the pharmacokinetics of medications used …

Posted in 2015 Volume 14 – Issue 3

Laparoscopic box simulators constitute an accessible, affordable and effective solution for training in laparoscopic surgery

Litos Michail, Siristatidis Charalampos, Chrelias Charalampos, Grammatikakis Ioannis, Trompoukis Pantelis, Papantoniou Nikolaos

Background: Acquisition of laparoscopic surgical skills is best achieved before entering the operating theatre, in the context of a simulated environment. Although mechanical simulators are affordable and effective training tools, they remain non available in many training institutions. This study investigates the options available and the cost for purchasing a mechanical laparoscopic …

Posted in 2015 Volume 14 – Issue 3 Tagged , , , ,

Vaginal misoprostol (Prostin®) for intrauterine insemination: A meta – analysis of randomized trials

Pergialiotis Vasilios, Frountzas Maximos, Stefanidis Konstantinos, Prodromidou Anastasia, Perrea Despina, Vlachos D Georgios

Introduction: The seminal fluid contains prostaglandins which seem to be important during the fertilization process. However, these are cleaved during semen preparation for intrauterine insemination (IUI). The purpose of the present meta – analysis is to investigate if vaginal application of prostaglandin E (PGE) improves the pregnancy rates among women undergoing IUI.

The endocrine and paracrine role of placental cytokines, growth factors and peptides

Vrachnis Nikolaos, Grigoriadis Charalampos, Zygouris Dimitrios, Vlachadis Nikolaos, Antonakopoulos Nikolaos, Iliodromiti Zoe

The human placenta plays a major role in pregnancy as it is the main organ of communication between the mother and the fetus. One of its actions is the secretion of a variety of substances. Cytokines, growth factors and peptides are secreted by the placenta during pregnancy and may act via endocrine, autocrine and paracrine pathways. Cytokines promote trophoblast implantation as well …

Posted in 2015 Volume 14 – Issue 2 Tagged , , ,

Abnormal cytologic findings during pregnancy

Michail Georgios, Androutsopoulos Georgios, Georgantis Apostolos, Adonakis Georgios, Decavalas Georgios

Our aim was the illustration of the controversies that occur during pregnancy related to the mode of obtaining and interpreting a cervical smear, specific colposcopic features, as well as the approach of diagnosing, following- up and treatment, based on the findings of the Papanicolaou smear. A review of the literature as well as the updated American Society of Colposcopy …

Posted in 2015 Volume 14 – Issue 2 Tagged , , ,

Exposure to ionizing radiation and pregnancy

Kathopoulis Nikolaos, Moirogiorgos Dimitrios, Thomakos Nikolaos, Rodolakis Alexandros

The exposure of pregnant women to ionizing radiation is often a source of concern and provokes many questions. This anxiety is often unjustified and the questions are asked too late. Ignorance of the subject is likely to harm the woman who requires investigative imaging or lead to inappropriate attitudes to offer a medical termination of pregnancy after low-level exposure …

Posted in 2015 Volume 14 – Issue 2 Tagged ,

Cesarean scar pregnancy: A diagnostic dilemma and management with suction curettage

Syed Rifat, Sinha Prabha, El – Halwagy Hosam, Brompton Wendy

A case of a cesarean section scar pregnancy with a diagnostic dilemma is presented. Due to a decrease in β – hCG after 48 hours, the patient was diagnosed with a failing pregnancy and was given misoprostol. However, β – HCG was still high and the patient had a severe vaginal bleeding after a month of medical management. Evacuation curettage under laparoscop …

Posted in 2015 Volume 14 – Issue 2 Tagged , , , , ,

The impact of current obstetric practice on temporal patterns of childbirth

Sakellariou Vasiliki, Dritsakou Kalliopi, Tzortzi Alexandra, Nousia Konstantina, Farmakides George

Introduction: The actual time of spontaneous delivery has been a matter of investigation for many years by anthropologists and physicians. The aim of this study was to test the possible associations between gestational age, mode, day, duration and time of delivery. Material and Methods: This was an observational study of 412 women given birth in our maternity hospital that were recruited …

Posted in 2015 Volume 14 – Issue 3 Tagged , ,

Greek – language Clinical Guidelines and Consent Forms in Obstetrics and Gynecology developed by the HSOG

Vrachnis Nikolaos, Loufopoulos Aristotelis, Tarlatzis Vasileios

The Hellenic Society of Obstetrics and Gynecology (HSOG) has published, with a great sense of responsibility and pride, the first set of Guidelines and Consent Forms in Obstetrics and Gynecology in the Greek language. With evidence – based medicine nowadays becoming increasingly important …

Posted in 2015 Volume 14 – Issue 1

Gonadotropin surge attenuating factor: Α physiological regulator

Messinis Ioannis, Messini Christina, Dimitraki Marina, Anifandis George, Dafopoulos Konstantinos

Gonadotropin surge attenuating factor (GnSAF) is a non- steroidal ovarian substance, which attenuates the endogenous LH surge in superovulated women. Although several attempts have been made to purify GnSAF from various biological materials, different sequences were found. Only one of them has shown substantial homology of GnSAF to a known portion of the human genome …

Posted in 2015 Volume 14 – Issue 1 Tagged , , , ,