Editorial

Dimitris Loutradis

Gynecological cancers, including cervical, endometrial, ovarian, vaginal, and vulvar cancers, pose a significant threat to women’s health. The incidence of these malignancies has been reported to be on the rise, with an increase in the number of registered patients for all gynecological malignancies …

Mucinous differentiation of endometrioid endometrial carcinoma: Impact on pathology features and survival outcomes

Vasilios Pergialiotis, Dimitrios Haidopoulos, Vasilios Lygizos, Dimitrios Efthimios Vlachos,  Ioannis Rodolakis, Aikaterini Dimopoulou, Kalliroi Goula, Nikolaos Thomakos

Objective: Mucinous differentiation of endometrioid adenocarcinoma refers to the presence of a mucinous component that does not exceed 50% of the surface of the tumor. It has been associated with improved survival outcomes. In the present systematic review, we summarize the evidence to provide a robust result concerning the prognostic significance of this histologic variant …

Association of Vitamin-D insufficiency and infertility: A Literature Review

Sofoklis Stavros, Anastasios Potiris, Sofia Sgourali, Εirini Drakaki, Despoina Mavrogianni,  Ekaterini Domali, Peter Drakakis

Vitamin D receptors are present in both male and female central neural system and reproductive system hence Vitamin D sufficiency or insufficiency affects fertility. The present review aims to determine a correlation between Vitamin D insufficiency and infertility. Regarding female infertility, it was found that Vitamin D insufficiency is associated with increased issues during conception and higher miscarriage rate …

Infertility and female sexual dysfunction: A literature review

Garyfalia Bitsis, Ekaterini Domali, Eirini Drakaki, Peter Drakakis, Sofoklis Stavros

Fertility is a fundamental component of women’s quality of life as it still seems to reflect feminine identity and adequacy of their social role. According to the World Health Organization (WHO), infertility is defined as the failure to conceive after one year of unprotected sexual intercourse in women younger than 35 year and after 6 months in women older than 35 years old …

Management of borderline ovarian tumors: A retrospective study in Northern Greece

Kyriaki Mitta, Ioannis Tsakiridis, Akriola Fachiridou, Fotios Zachomitros, Themistoklis Dagklis, Apostolos Mamopoulos, Apostolos Athanasiadis, Ioannis Kalogiannidis

Introduction: Borderline ovarian tumors (BOTs) are tumors of low malignant potential commonly presented in women of reproductive age. Their incidence has been increasing over the years and issues regarding fertility preservation are very crucial …

Comparative assessment of veneral disease research laboratory (VDRL) and point of care (POC) tests for diagnosing syphilis among pregnant women at a tertiary health facility in Lagos: A retrospective cohort study

Nkechinyere Harrison, Aloy Okechukwu Ugwu, K.S. Okunade, Lawal Ismail, Olufemi Ayanbode, Elekwa Chinenye, E.P. Igbodike, A.A. Oluwole, O.A. Kusamotu, R.F. Anas, Nneoma K. Ani-Ugwu, Awoniyi Adebayo Williams, Alakija Oluwaseun, C.J. Okeke, Ajani Taiwo, O. Ngwu Hilary, Okoye Chinelo, Aisini Abigail Oghenefejiro, Orjiakor Chioma Gloria, S. Ige,  Chibunna Denzel Ezeoke, Ogbekhuemen Martha Aidevo

Background: Syphilis is a systemic infection caused by the Spirochete Treponema Pallidum. The infection is of particular concern during pregnancy because of the high risk of vertical transmission causing adverse outcome including death. Traditional screening method is with Venereal Disease Research Laboratory (VDRL), which has a high false positive result and an increased waiting time …

Hemostatic Effect of Intrauterine Instillation of Oxytocin in Hysteroscopic Myomectomy: A Randomized Double Blinded Control Trial

Walid Hitler Ahmed Tantawy, Ahmed Mohamed Mamdouh, Amir Hamdy Abd El-Hady Mahfouz, Mahmoud Mohamed Ghaleb

Pubic sIntroduction: Uterine myomas are benign, smooth muscle tumors of the uterus that are affected by estrogen and progesterone. Most fibroids are asymptomatic and require no intervention or further investigations. Fibroids arise from the uterine smooth muscles then migrate to a place of lower resistance becoming subserosal or submucous myomas or remains intra-myometrial …

Indication-based administration of low dose aspirin for the prevention of preeclampsia: A retrospective study in Northern Greece

Ioanna Vagioni, Kyriaki Mitta, Ioannis Tsakiridis, Themistoklis Dagklis, Apostolos Athanasiadis, Apostolos Mamopoulos

Preeclampsia is a multisystem progressive disorder characterized by vascular abnormalities and coagulation disorders. The administration of low-dose aspirin is recommended before 16 weeks to delay or even avoid the onset of preeclampsia, based on screening tests. This study aimed to investigate the targeted or non-targeted administration of low-dose aspirin in pregnancies, according to the indications for its administration …

Solitary lymph-nodal para-aortic recurrence in a patient with High Grade Serous Ovarian Cancer

Maria Fanaki, Paraskevas Perros, Vasilios Pergialiotis, Konstantinos Mpramis, Nikolaos Thomakos

Ovarian cancer is the second most common cause of gynecologic cancer death. The most common histologic category of epithelial ovarian cancer is High Grade Serous Ovarian Cancer (HGSOC). The initial management usually involves appropriate staging and debulking surgery. Otherwise, patients with unresectable disease receive neoadjuvant chemotherapy, and then undergo Interval Debulking Surgery (IDS) …