Gonadotropin surge attenuating factor: Α physiological regulator

Messinis Ioannis, Messini Christina, Dimitraki Marina, Anifandis George, Dafopoulos Konstantinos

Gonadotropin surge attenuating factor (GnSAF) is a non- steroidal ovarian substance, which attenuates the endogenous LH surge in superovulated women. Although several attempts have been made to purify GnSAF from various biological materials, different sequences were found. Only one of them has shown substantial homology of GnSAF to a known portion of the human genome …

Posted in 2015 Volume 14 – Issue 1 Tagged , , , ,

Ovarian regulation of gonadotropin secretion

Dafopoulos KC, Kallitsaris A, Messinis IE

Hypothalamus is the main regulator of reproductive function, responding to both peripheral and central nervous system messages and exerting its influence by means of neurotransmitters transported to the pituitary. Steroidal and non-steroidal ovarian hormones also play a substantial role in the normal reproductive function. During the follicular phase of the normal menstrual cycle …

Posted in 2004 Volume 3 – Issue 4 Tagged , , , ,