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Placental eicosanoids as endocrine and paracrine mediators during pregnancy

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Iliodromiti Zoe, Grigoriadis Charalampos, Stournaras Stamatis, Daniilidis Angelos, Dafopoulos Konstantinos, Vrachnis Nikolaos

Eicosanoids, biologically active molecules possessing a wide range of functions, include prostaglandins, thromboxanes and leukotrienes. During pregnancy, eicosanoids are produced by the chorionic membranes and the decidua as well as by the placenta. The eicosanoids play an important role throughout pregnancy. During implantation, they enable the trophoblast to invade and colonize …

Posted in 2014 Volume 13 – Issue 1 Tagged , , , ,

Management of women with cytological glandular lesions of uterine cervix: New literature data

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Nikolaou Marinos, Papadimitriou Ifigenia, Michail George, Androutsopoulos George, Adonakis George, Relakis Konstantinos, Decavalas George

The incidence of cervical glandular lesions has significantly increased during the past two decades especially among young women. This rise in registered cases is predominantly attributed to this entity’s rising prevalence as well as recent advances in cytology. Atypical glandular cells identified by secondary cervical screening (Papanicolaou) might actually harbor significant …

Posted in 2014 Volume 13 – Issue 1 Tagged , ,

Microscopic hematuria in the gynecologic and obstetric patient

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Lazarou George, Stournaras Stamatios, Nousia Konstantina, Zygouris Dimitrios

Microscopic hematuria is a common finding in urinalysis during gynecological – obstetric control. We present the case of a 58 years old woman with recurrent hematuria in annual gynecological check. The literature review highlights a series of tests that must be carried out to investigate these cases. Medical history and physical examination are the first steps approach to identify …

Posted in 2014 Volume 13 – Issue 1 Tagged , ,

Struma ovarii in combination with increased levels of CA125 and ascites: Case report and review of the literature

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Kougioumtsidou Anna, Kougioumtsidou Niki, Athanasopoulou Maria, Pados George, Tarlatzis Vasileios

Ovarian goiter is a rare tumor of the ovary that is characterized by a presence of thyroid tissue in the ovary and occupies more than 50% of the total mass of the tumor. It is accompanied by ascites in the 1/3 of cases. Τhe combination of struma ovarii, ascites and increased levels of CA125 is extremely rare. We report a case of a 77 years old woman with ascites, a big mass …

Posted in 2014 Volume 13 – Issue 1 Tagged , , , ,

Is preventive storage of cord blood justified and why is it not yet widely prescribed?

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Karavanas George

Discussion around cord blood stem cells is not new in Greece. Sadly the discussion has been focused mainly in the model of storage that would be preferable (public banking vs family banking) and far less in the possible medical applications of cord blood itself. It’s important to notice however, that the vast quantity of cord blood in today’s Greece …

Posted in 2014 Volume 13 – Issue 1

Medications in pregnancy: challenges and concerns

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Vrachnis Nikolaos, Loufopoulos Aristotelis

Pregnancy is a physiological condition in which drug treatment is a particularly delicate issue, since many medications can cross the blood – placental barrier and potentially cause harm to the fetus. In addition, the physiological changes in pregnancy can negatively affect the pharmacokinetics of medications used …

Posted in 2015 Volume 14 – Issue 3

Laparoscopic box simulators constitute an accessible, affordable and effective solution for training in laparoscopic surgery

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Litos Michail, Siristatidis Charalampos, Chrelias Charalampos, Grammatikakis Ioannis, Trompoukis Pantelis, Papantoniou Nikolaos

Background: Acquisition of laparoscopic surgical skills is best achieved before entering the operating theatre, in the context of a simulated environment. Although mechanical simulators are affordable and effective training tools, they remain non available in many training institutions. This study investigates the options available and the cost for purchasing a mechanical laparoscopic …

Posted in 2015 Volume 14 – Issue 3 Tagged , , , ,

Vaginal misoprostol (Prostin®) for intrauterine insemination: A meta – analysis of randomized trials

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Pergialiotis Vasilios, Frountzas Maximos, Stefanidis Konstantinos, Prodromidou Anastasia, Perrea Despina, Vlachos D Georgios

Introduction: The seminal fluid contains prostaglandins which seem to be important during the fertilization process. However, these are cleaved during semen preparation for intrauterine insemination (IUI). The purpose of the present meta – analysis is to investigate if vaginal application of prostaglandin E (PGE) improves the pregnancy rates among women undergoing IUI.

The endocrine and paracrine role of placental cytokines, growth factors and peptides

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Vrachnis Nikolaos, Grigoriadis Charalampos, Zygouris Dimitrios, Vlachadis Nikolaos, Antonakopoulos Nikolaos, Iliodromiti Zoe

The human placenta plays a major role in pregnancy as it is the main organ of communication between the mother and the fetus. One of its actions is the secretion of a variety of substances. Cytokines, growth factors and peptides are secreted by the placenta during pregnancy and may act via endocrine, autocrine and paracrine pathways. Cytokines promote trophoblast implantation as well …

Posted in 2015 Volume 14 – Issue 2 Tagged , , ,

Abnormal cytologic findings during pregnancy

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Michail Georgios, Androutsopoulos Georgios, Georgantis Apostolos, Adonakis Georgios, Decavalas Georgios

Our aim was the illustration of the controversies that occur during pregnancy related to the mode of obtaining and interpreting a cervical smear, specific colposcopic features, as well as the approach of diagnosing, following- up and treatment, based on the findings of the Papanicolaou smear. A review of the literature as well as the updated American Society of Colposcopy …

Posted in 2015 Volume 14 – Issue 2 Tagged , , ,

Exposure to ionizing radiation and pregnancy

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Kathopoulis Nikolaos, Moirogiorgos Dimitrios, Thomakos Nikolaos, Rodolakis Alexandros

The exposure of pregnant women to ionizing radiation is often a source of concern and provokes many questions. This anxiety is often unjustified and the questions are asked too late. Ignorance of the subject is likely to harm the woman who requires investigative imaging or lead to inappropriate attitudes to offer a medical termination of pregnancy after low-level exposure …

Posted in 2015 Volume 14 – Issue 2 Tagged ,

Cesarean scar pregnancy: A diagnostic dilemma and management with suction curettage

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Syed Rifat, Sinha Prabha, El – Halwagy Hosam, Brompton Wendy

A case of a cesarean section scar pregnancy with a diagnostic dilemma is presented. Due to a decrease in β – hCG after 48 hours, the patient was diagnosed with a failing pregnancy and was given misoprostol. However, β – HCG was still high and the patient had a severe vaginal bleeding after a month of medical management. Evacuation curettage under laparoscop …

Posted in 2015 Volume 14 – Issue 2 Tagged , , , , ,

The impact of current obstetric practice on temporal patterns of childbirth

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Sakellariou Vasiliki, Dritsakou Kalliopi, Tzortzi Alexandra, Nousia Konstantina, Farmakides George

Introduction: The actual time of spontaneous delivery has been a matter of investigation for many years by anthropologists and physicians. The aim of this study was to test the possible associations between gestational age, mode, day, duration and time of delivery. Material and Methods: This was an observational study of 412 women given birth in our maternity hospital that were recruited …

Posted in 2015 Volume 14 – Issue 3 Tagged , ,

Greek – language Clinical Guidelines and Consent Forms in Obstetrics and Gynecology developed by the HSOG

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Vrachnis Nikolaos, Loufopoulos Aristotelis, Tarlatzis Vasileios

The Hellenic Society of Obstetrics and Gynecology (HSOG) has published, with a great sense of responsibility and pride, the first set of Guidelines and Consent Forms in Obstetrics and Gynecology in the Greek language. With evidence – based medicine nowadays becoming increasingly important …

Posted in 2015 Volume 14 – Issue 1

Gonadotropin surge attenuating factor: Α physiological regulator

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Messinis Ioannis, Messini Christina, Dimitraki Marina, Anifandis George, Dafopoulos Konstantinos

Gonadotropin surge attenuating factor (GnSAF) is a non- steroidal ovarian substance, which attenuates the endogenous LH surge in superovulated women. Although several attempts have been made to purify GnSAF from various biological materials, different sequences were found. Only one of them has shown substantial homology of GnSAF to a known portion of the human genome …

Posted in 2015 Volume 14 – Issue 1 Tagged , , , ,