Galanopoulos NG1, Galazios G2, Rogganaki AB1, Kontomanolis E2
Anti-inflammatory and immunosuppressive drugs in rheumatic diseases and fertility, pregnancy and lactation
Group B streptococcus infection and pregnancy
Sifakis S, Kappou D, Botsis D
Group B streptococcus (GBS) consists a leading cause of neonatal mortality and morbidity, because it is the most frequent cause of neonatal sepsis and meningitis in the developed countries. GBS infection in infants is classified into early-onset disease, which occurs within the first week of life, and late-onset disease. GBS colonization of the genital and lower gastrointestinal tracts …
Melanoma, female hormones and pregnancy
Ioannides C
Malignant melanoma has been linked to female hormones and pregnancy. Despite some existing controversy, it is generally accepted that administration of contraceptives and hormonal replacement therapy is not contraindicated in women with a history of melanoma. Female patients should postpone pregnancy for two-three years post treatment. Pregnancy does not seem to negatively influence …
Live birth after polar body biopsy and preimplantation genetic screening of aneuploidy by DNA-microarray comparative genomic hybridisation
Economou K, Christopikou D, Tsorva E, Handyside A, Cazlaris H, Davies S, Mastrominas M
Α patient with a history of recurrent IVF failures was subjected to preimplantation genetic screening of aneuploidies by DNA microarray comparative genomic hybridisation (a-CGH). Oocytes that had been screened and found chromosomally euploid after biopsy of the first and second polar bodies were used, thereby avoiding the use of donated oocytes. A twin clinical pregnancy was achieved …
Total or subtotal abdominal hysterectomy in benign gynecological conditions: How, why, when?
Daniilidis Α, Spathopoulou S., Dinas Κ, Τantanasis T, Κartsea F, Giannoulis C, Balaouras D, Foteinakis I,Μakris V, Loufopoulos Α
Total and subtotal abdominal hysterectomy for benign indications have been compared in randomized clinical trials and observational studies. The aim of this review was to compare total and subtotal hysterectomy concerning incontinence, cervical stump problems, operation time, postoperative complications, quality of life, and prolapse. Incontinence, prolapse and cervical stumps problems …
Pregnancy in patients with rheumatoid arthritis
Fertility-sparing surgical options in patients with early cervical cancer: Radical vaginal or abdominal trachelectomy?
Pigis D, Thomakos N, Lourantou D, Rodolakis A, Antsaklis A
Radical trachelectomy has emerged over the last years as a reasonable fertility-sparing operation for selected patients with stage I cervical cancer. The aim of this review was to summarize the latest literature and outline patient selection criteria, operative and oncologic outcomes. The majority of studies on fertility-sparing procedures in early stage cervical cancer examined …
Epithelial ovarian cancer of low malignant potential in a 15 year old patient: A case report
Ravanos Κ, Kologiannidis I, Tsertanidou A, Flaris N, Agorastos T
Epithelial ovarian cancer is extremely rare in adolescence but must be included in the differential diagnosis of an ovarian mass. Most patients present with early stage tumors of low malignant potential and achieve favorable overall survival. Preservation of fertility is essential, therefore conservative treatment is recommended according to oncological guidelines …
Pregnancy and breast cancer
Evangelinakis N, Polyzou E, Grammatikakis I, Kassanos D
Breast cancer is the second leading cause of death from cancer in women during pregnancy. Pregnancy-associated breast cancer presents a challenging clinical situation because of the special and unique circumstances surrounding the growth and differentiation of the developing fetus. The trend towards later age at first childbirth has resulted in an increase in the number of breast cancer …
Female urinary incontinence: A modern approach
Farfaras A, Zografos G, Litos M, Antoniou S
Female urinary incontinence is a common problem with important consequences. Its prevalence and severity have been underestimated, and its management has been inconsistent. The scientific and technical advances of the recent years have provided effective treatment options and have established urogynecology as a subspecialty. Urge incontinence results from bladder overactivity …
Breast abscesses
Ioannides C
Breast abscesses are classified into lactational-related and those which are not associated with lactation. They are infrequent, however, they can cause considerable morbidity. The diagnosis is mainly clinical. They are treated with ultrasound assisted aspiration or, occassionally, with incision and drainage. If there is suspicion of malignancy, an incisional biopsy of the abscess …
Surgical management of breast tuberculosis: Diagnostic and therapeutic approach
Marinopoulos S1, Gatzionis T1, Papaspyrou I2, Dimitrakakis C1, Antsaklis A1
Mammary (breast) tuberculosis is a rare manifestation of extra-pulmonary disease, which accounts for less than 0.1% of breast diseases in developed countries, but reaches 3-4% in endemic areas (India, Africa). It mostly appears in women of reproductive age, multiparous or lactating. It has been scarcely reported to infect male patients, mainly before puberty, as well as women …
Current knowledge on common molecular mechanisms involved in endometriosis and tumor metastasis
Timologou A, Ζafrakas Μ, Grimbizis G, MiliarasD, Kotronis K, Tarlatzis Β
Although several theories exist, the etiology and pathogenesis of endometriosis is poorly understood. Data from clinical and laboratory studies indicate that this disease has common characteristics with malignant neoplasms. The present review focuses on the common molecular mechanisms involved in both implantation of tissue at ectopic sites in endometriosis and tumor metastasis …
Gastrointestinal and vascular damage during total laparoscopic hysterectomy: A review of the literature
Katsakos I, Karpeta M, Paraskevaidis C, Papadis P, Paparistidis N
The following review examines the current role and complication rates of total laparoscopic hysterectomy (TLH), which is a hysterectomy completed entirely laparoscopically. Recent advances in equipment, surgical techniques and training have established total laparoscopic hysterectomy as a well tolerated and efficient technique. It is increasingly being adopted around the world …
Current management of gestational trophoblastic disease
Zacharakis D, Thomakos N, Rodolakis A, Antsaklis A
Gestational trophoblastic disease comprises a spectrum of interrelated conditions originating from the placenta. These conditions are classified as gestational trophoblastic disease (GTD), when they present a benign behaviour and as gestational trophoblastic neoplasia (GTN), when a malignant potential is present. Vaginal bleeding and hyperemesis gravidarum are the most common presenting …