Preimplantation Genetic Diagnosis

Loutradis Dimitris

A benefit of the state-of-the-art in assistant reproductive treatment requires among others, a definitive preimplantation genetic diagnosis (PGD) as an alternative to prenatal diagnosis, for couples with a family history of a genetic disease. In the past, parents had to take the risk for an inherited genetic disorder, or undergo prenatal diagnostic testing and pregnancy termination …

Posted in 2017 Volume 16 – Issue 3

First live birth in Greece after blastocyst trophectoderm biopsy and preimplantation genetic diagnosis by karyomapping

Economou A.K , Wells D, Christopikou D, Tsorva E, Davies S, Mastrominas M

Preimplantation genetic diagnosis for single gene defects is a well established tool in assisted reproduction. Karyomapping is a genome-wide parental haplotyping technology using a high density single nucleotide polymorphism array that allows the diagnosis of any single gene defects and the majority of aneuploidies from the same embryonic sample post embryo biopsy. A couple, carriers of different cystic fibrosis (CF) mutations …

Posted in 2017 Volume 16 – Issue 3 Tagged , , ,

Assisted Reproduction Techniques; What’s old and what’s new

Panagakis G, Asimakopoulos G, Sfakianakis A, Theofanakis Ch, Kallianidis K, Drakakis P

The greatest achievement of assisted reproductive medicine was the birth of Louise Brown in 1978. It was the result of many efforts by Edwards & Steptoe to achieve pregnancy with in vitro fertilization (IVF). Since then, there has been a rapid development of assisted reproduction techniques, with the ultimate aim of making infertility treatment more effective and affordable for most couples. The thorough study …

Posted in 2017 Volume 16 – Issue 3 Tagged

Surveillance of breast cancer patients following primary therapy

Rellias I, Marinopoulos S, Zagouri F, Dimitrakakis C

Objective: To offer a summary of evidence-based recommendations for the surveillance of breast cancer patients after primary treatment. Quality of evidence: A literature search was conducted in Pubmed/MEDLINE using the terms: breast cancer, follow-up, surveillance, survivorship, guidelines and survivorship care plans, with focus on review of recent guidelines published by major cancer organizations…

Posted in 2017 Volume 16 – Issue 3 Tagged , , ,

Can the measurement of endometrial thickness by transvaginal ultrasound be used for the prediction of endometrial cancer in asymptomatic post-menopausal women? A systematic review of the literature

Daniilidis A, Balaouras D, Chitzios D, Sardeli C, Mamopoulos A, Assimakopoulos E

Aim: To assess the diagnostic efficiency of TVS (transvaginal ultrasound measurement) for discrimination between benign and malignant endometrial conditions in asymptomatic postmenopausal women. Moreover, to evaluate the cut off risk…

Posted in 2017 Volume 16 – Issue 3 Tagged , , , , , ,

Ovarian cysts in pregnancy. When surgical treatment required and when monitoring preferred?

Kalmantis K, Petsa A, Alexopoulos E, Daskalakis G, Rodolakis A

Introduction: Ovarian cysts occur in 3% of pregnancies. Usually, they do not have clinical symptoms and are found accidentally during the ultrasound screening performed in the 1st trimester of pregnancy. Materials and Methods: Articles were identified through electronic databases; no date or language restrictions were placed; relevant citations were hand searched. The search was conducted using the following terms …

Posted in 2017 Volume 16 – Issue 3 Tagged , , , , ,

Prediction of Gestational Diabetes Mellitus in the first trimester of pregnancy

Eleftheriades M, Karopoulou E, Papastefanou I, Kappou D, Sotiriadis A, Chrousos G

Gestational diabetes mellitus (GDM) is defined as any degree of carbohydrate intolerance with onset or first recognition during pregnancy. This entity has been increasing in prevalence and has been associated with various maternal and perinatal adverse outcomes. There is much controversy about the diagnostic criteria and management of GDM and current screening models are based on maternal and obstetric characteristics …

Posted in 2017 Volume 16 – Issue 2 Tagged , , , , , ,

Comparative study of endometrial imaging and cytologic evaluation in perimenopause for the timely diagnosis of endometrial cancer

Vaitsi V, Moschaki V, Chatzistamatiou K, Tsertanidou A, Athanatos D, Athanasiou Ε, Loufopoulos Α, Tarlatzis Β, Agorastos T

Ιntroduction: The aim of the present study was to determine the diagnostic accuracy of sono – hysterography alone or combined with liquid-based cytology (LBC) of endometrium for endometrial lesions detection in perimenopausal women with abnormal uterine bleeding (AUB)…

Posted in 2017 Volume 16 – Issue 2 Tagged , , ,

Mobile Cystoscope

Chatzipapas I., Kathopoulis N., Protopapas A., Kyritsis N., Vlachos D. E., Loutradis D.

Introduction: The purpose of this study was to evaluate the feasibility and clinical outcome of a new setup for cystoscopy using mobile technology. Materials and Methods: A total of 20 women with indications of cystoscopy were examined according to the new setup using smartphone and portable led light sources and the standard cystoscopic setup. The image quality as far as it concerns the ability to end up with a correct diagnosis …

Posted in 2017 Volume 16 – Issue 2 Tagged , , , ,