Editorial: Advancing women’s health through integration of clinical innovation, translational research, and patient-centered care

Dimitris Loutradis

The current issue of the Hellenic Journal of Obstetrics and Gynecology highlights the remarkable breadth of contemporary research in women’s health, encompassing basic science, clinical obstetrics, gynecologic surgery, pelvic floor medicine, bioethics, and systematic evidence synthesis …

Association of Kidney Injury Molecule-1 (KIM-1) levels in urine with preeclampsia

Muhammad Risal Djalika, Efendi Lukas, Sriwijaya Qadar, Firdaus Hamid, Ananda Mardiah Prefitri, Fatmawati Madya

Introduction: Preeclampsia is a major hypertensive disorder of pregnancy and a leading cause of maternal and perinatal morbidity and mortality worldwide. Kidney Injury Molecule-1 (KIM-1) has emerged as a promising biomarker of early renal tubular injury; however, its association with severe preeclampsia remains insufficiently established …

Risk evaluation of air travel in pregnant women according to gestational trimester: A Systematic Review based on observational studies

Donel Suhaimi, Renardy Reza Razali, Sofyan Andri, Kalvin Tutamana Hutabarat

Background: Air travel during pregnancy has become increasingly common in line with the rising mobility of women of reproductive age. Although generally considered safe for uncomplicated pregnancies, potential risks may vary across different trimesters …

Decoding the molecular pathways of Ricinus communis in labor induction: A Reverse Pharmacology Insight

Sanika Aphale, Sumedh Joshi, Swati Gaikwad, Meenakshi Pandey, Sujata Kadam

Background: Seed Oil of herb Ricinus communis L. (commonly known as castor oil or Eranda Taila in sanskrit) has traditionally been used to induce labor. However, its mode of action as well as underlying molecular mechanisms remain unclear. In alignment with the principles of reverse pharmacology …

Impact of fetal gender on the incidence of preeclampsia: A cohort study in Greece

Elisavet Lailisidou, Antigoni Tranidou, Apostolos Mamopoulos, Themistoklis Dagklis, Ioannis Tsakiridis

Introduction: Preeclampsia is associated with significant maternal and fetal morbidity and mortality, with established risk factors. Fetal gender has been proposed as a potential independent risk factor for preeclampsia, though its exact role is not yet determined as studies to date have reported conflicting results …

Association between grade 3 and 4 pelvic organ prolaps and anxiety based on cortisol levels

Muhammad Furqon Fahluly, Imam Ahmadi Farid, Samrichard Rambulangi, David Lotisna, Sriwijaya

Introduction: Higher degrees of Pelvic organ prolapse (POP) (grades 3 and 4) are often associated with anxiety, which can reduce quality of life. The aim of this study was to determine the association between grades 3 and 4 pelvic organ prolapse and anxiety symptoms, as assessed by serum cortisol levels …

Correlation vaginal microbiota and risk factor on pelvic organ prolapse

Wahidah Masrah, Elizabet C. Jusuf, David Lotisna, Nuraini Abidin, St. Nur Asni, Firdaus Hamid

Background: Pelvic organ prolapse (POP) is a common pelvic floor disorder that markedly affects women’s quality of life. Recent evidence suggests that vaginal microbiota imbalance may play a role in pelvic floor dysfunction; however, its association with POP risk factors remains poorly understood …

Effect of dextrose normal saline vs normal saline on the progress of labour – prospective observational study

Chandrasekar Jahnavi, Meena Thinnanur Sundarraj, Minthami Sharon, Logeswari BM

Background: Labour is a physiologically demanding process requiring sustained energy expenditure by the myometrium. While intravenous hydration is routinely provided, the optimal composition of intrapartum fluids remains uncertain. This study aimed to evaluate the effect of intravenous dextrose normal saline compared to normal saline …

Laparoscopic treatment of ovarian pregnancy: A Scoping Review

Georgios Sourlas, Konstantinos Pantazis, Menelaos Lampropoulos, Angelos Daniilidis

Objective: Ovarian ectopic pregnancy is a rare but potentially life-threatening condition that may lead to severe hemorrhage if misdiagnosed or left untreated. Reported frequency of ovarian pregnancy is 0.5%–1% of all extra-uterine gravidities, accounting for about 0.5–3% of all ectopic pregnancies …

Wrongful life (bioethical and legal implications)

Ioannis Pantazis, Rafailia Boufikou, Christina Kakourou, Dimitra Chrysafi, Nikolaos Dagklis, Maria Milapidou

Prenatal screening is a critical process that aims to diagnose genetic, chromosomal and other fetal abnormalities early. However, there are cases in which mistakes can occur, with serious consequences for both the parents and the child. This prenatal misdiagnosis can lead to the physician’s criminal and civil liability …