Tag: meta-analysis

The impact of frailty on treatment strategies and survival outcomes of vulvar cancer patients: a systematic review

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Vasilios Pergialiotis, Maria Fanaki, Antonia Varthaliti, Vasilios Lygizos, Dimitrios Haidopoulos, Nikolaos Thomakos

Background: Vulvar cancer is an uncommon gynecologic malignancy that is usually manifested in older ages which have several comorbidities. Frail patients pose a significant subgroup in gynecologic oncology as frailty may affect treatment plans and result in significant reduction of survival outcomes. In the present systematic review we summarize current evidence focusing on the impact of frailty in vulvar cancer patients …

Mucinous differentiation of endometrioid endometrial carcinoma: Impact on pathology features and survival outcomes

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Vasilios Pergialiotis, Dimitrios Haidopoulos, Vasilios Lygizos, Dimitrios Efthimios Vlachos,  Ioannis Rodolakis, Aikaterini Dimopoulou, Kalliroi Goula, Nikolaos Thomakos

Objective: Mucinous differentiation of endometrioid adenocarcinoma refers to the presence of a mucinous component that does not exceed 50% of the surface of the tumor. It has been associated with improved survival outcomes. In the present systematic review, we summarize the evidence to provide a robust result concerning the prognostic significance of this histologic variant …

Posted in 2023 Volume 22 – Issue 4 Tagged , , ,

Comparison of survival outcomes among patients with uterine carcinosarcoma and those with grade 3 uterine carcinoma: A systematic review of the literature

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Vasilios Pergialiotis, Nikolaos Thomakos, Nikol-Natalia Armata, Efthimia Eirini Gkotsi, Andreas Konstantinos Gousias, Ioanna Kaisari, Marianna Marra, Alexandros Rodolakis, Dimitrios Haidopoulos

Introduction: Endometrial carcinosarcoma is an aggressive form of cancer that has been classified in type II endometrial carcinomas. However, survival outcomes seem to differ considerably compared to grade 3 endometrioid adenocarcinoma, the predominant form of cancer in this group of patients. The purpose of the present systematic review is to investigate overall and progression free survival in patients with endometrial carcinosarcoma to those of patients with grade 3 endometrioid adenocarcinoma …

Posted in 2022 Volume 21 – Issue 2 Tagged , , ,