Relationship of soluble Fms-like tyrosine kinase 1, soluble endoglin, placental growth factor blood levels with the severity of late onset preeclampsia

Ethem Serdar Yalvac, Mustafa Kara, Emre Baser, Taylan Onat, Melike Demir Caltekin, Müjgan Ercan, Demet Aydogan Kirmizi

Purpose: Preeclampsia (PE) is a pregnancy-specific syndrome characterized by placentation disorder that increases maternal and fetal morbidity and mortality. Overproduction of anti-angiogenic factors such as soluble fms-like tyrosine kinase receptor 1 (sFlt-1) and soluble endoglin (sEng) and low production of placental growth factor (Pgf) from angiogenic factors contribute to preeclampsia pathogenesis …

Posted in 2021 Volume 20 – Issue 3 Tagged , , ,

The action of VEGF in angiogenesis

Ralli C, Kontomanolis E., Liberis V

Angiogenesis is a complicated process where new blood vessels are being formed from already pre-existing vessels. For tumor growth and metastases to distant organs, angiogenesis is a biological prerequisite. Tumor cells produce angiogenic factors, including Vascular Endothelial Growth Factor( VEGF), basic Fibroblast Growth Factor (bFGF), Platelet-Derived Endothelial Cell Growth Factor (PD-ECGF) …

Posted in 2012 Volume 11 – Issue 3 Tagged , , ,