The role of Kifc1, Kchn5 and miRNA-302 on in vitro development in 8-cell, morula and blastocyst stage of mouse embryos

Konstantinos Ntzeros, Despoina Mavrogianni, Athina Koutsi, Antonia Kandaraki, Anastasios Papadelas, Sofoklis Stavros, Petros Drakakis, Dimitrios Loutradis

 

 

Introduction: Embryo development is characterized by lack of cell cycle check-points and overexpression of core circadian oscillators. On previous report we have identified several genes over-and under-detected at human embryo blastomeres. In this study, we investigated the expression profile of Kcnh5, KIFC1 and miRNA-302 genes at three pre-implantation stages of mouse embryo development. Material and methods: Total RNA was extracted from mouse embyos at 8-cell, morula and blastocyst stage…

Posted in 2019 Volume 18 – Issue 3 Tagged , , , , ,