Methodological validation and pilot evaluation of apoptosis-related microRNAs in human cumulus cells as candidate biomarkers of embryo quality in IVF

Tsorva Erikaiti, Kakourou Georgia, Christopikou Dimitra, Davies Stephen, Zacharia Stavroula, Sfontouris Ioannis, Makrakis Evangelos, Frysira Helen, Tzetis Maria, Mastrominas Minas, Traeger-Synodinos Joanne

Background: Embryo selection remains one of the principal determinants of success in assisted reproductive technology (ART). Current selection methods rely primarily on morphological assessment, which provides only indirect and imperfect prediction of embryo developmental competence and implantation potential …