Garas A, Kallitsaris A, Messsinis IE
Estrogens are predominant regulators of gonadotrophin secretion during the reproductive years. However, the descriptions of a gene encoding a second type of estrogen receptor, termed ER-β, has prompted a reexamination of the estrogen signaling system and hence of the mechanisms that regulate the gonadotrophin secretion. Recent studies have shown that estrogens may also exert biological …