Evaluating the role of nuchal translucency in early detection of congenital defects: A systematic review

Elizabet C. Jusuf, Karloman A. Paipinan

Background: Nuchal translucency (NT) measurement is widely used in prenatal screening to detect chromosomal abnormalities, but its role in identifying congenital defect remains variably reported. Congenital heart disease (CHD) refers to structural malformations of the heart and/or great vessels, which predispose affected individuals to multiple morbidities across their lifespan and contribute to reduced long-term survival.. Although numerous studies have evaluated NT, none have specifically summarized…

Εvaluation of triple biochemical test in prenatal screening for chromosomal abnormalities

Rizos D, Hassiakos D, Botsis D, Kassanos D, Kolovos B, Sarandakou A, Salamalekis E, Creatsas G

The aim of this study was to present the results of prenatal screening for chromosomal abnormalities with the triple biochemical test in the second department of obstetrics and gynecology at Aretaieio hospital during an eight years period. In our hospital, the triple biochemical test (chorionic gonadotropin, alpha-fetoprotein and unconjugated estriol) in the second …

Posted in 2004 Volume 3 – Issue 2 Tagged , , , , , ,

Determining strategy of the non-invasive prenatal screening for chromosomal defects

Xiromeritis PN, Tsapanos VS

The need to reduce the rate of invasive screening (chorionic villous sampling, amniocentesis), and to detect the high risk pregnancies for chromosomal anomalies as early as possible, led to the concept of the sequential non-invasive screening, based on the Bayes theorem. The numerous non-invasive screening tests for chromosomal defects, should provide the calculation …

Posted in 2004 Volume 3 – Issue 1 Tagged , , Leave a comment