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First live birth in Greece after blastocyst trophectoderm biopsy and preimplantation genetic testing for hereditary angioedema

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Konstantinos A. Economou, Chrysanthi Billi, Lina Florentin, Anastasios Pachydakis, Ioannis Sintoris, Minas Mastrominas

Preimplantation genetic testing for monogenic/single-gene defects (PGT-M) is a well established tool in assisted reproduction. A couple, where the male was carrier of the c.550G>A (p.Gly184Arg) mutation of the SERPING 1 gene causing hereditary angioedema (HAE) attended our clinic for PGT-M. Employing a strategy of preserving embryos after blastocyst trophectoderm biopsy by vitrification cryopreservation …

Posted in 2021 Volume 20 – Issue 2 Tagged , , ,

“En caul birth” – A rare and spectacular delivery

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Konstantinos Zacharis, Eirini-Aikaterini Evangelopoulou, Konstantina Balafa, Eleni Chrysafopoulou, Aliki-Rafaella Papazisi, Ourania Koukoura

An en caul birth, also known as a “veiled birth” or “mermaid birth”, is when the baby is delivered completely enclosed within the unruptured amniotic sac (caul). There are exceptionally enchanting deliveries and said to be a token of good fortune. This phenomenon actually occurs in less than 1 in 80000 labors, rendering it extremely rare …

Posted in 2021 Volume 20 – Issue 2

The outbreak of COVID-19

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Loutradis Dimitris

The outbreak of COVID-19 has significantly affected our way of life during the last year. The scientific activity does not remain unaffected by this pandemic. Despite the continuous problems that arise during this period, the Hellenic Journal of Obstetrics and Gynecology has increased its efforts in attracting international as well Greek researchers in order to help establish its activity in the international literature. …

Posted in 2021 Volume 20 – Issue 1

Antimicrobial Prophylaxis for Caesarean Delivery; A comparative study between different agents

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Afroditi Ziogou, Ioannis Kokolakis, Fanourios Makrygiannakis, Antonis Makrigiannakis

Antimicrobial prophylaxis is commonly used for pre-intra and post-operative caesarean delivery. Caesarean delivery is still the single most important risk factor for puerperal infection. Post-caesarean infections include wound infections, endomyometritis, bacteraemia, septic shock, septic pelvic vein thrombophlebitis, necrotising fasciitis, pelvic abscess, dehiscence of the wound or evisceration. The goal of antimicrobial prophylaxis is to put a stop to postoperative infection …

Posted in 2021 Volume 20 – Issue 1 Tagged , ,

Evaluating multiple diagnostic tests: An application to cervical cancer

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Areti Angeliki Veroniki, Sofia Tsokani, Evangelos Paraskevaidis, Dimitris Mavridis

Systematic Reviews of diagnostic test accuracy (DTA) studies are increasingly comparing the accuracy of multiple tests to facilitate selection of the best performing test(s). Common approaches to compare multiple tests include multiple meta-analyses or meta-regression with the test type as a covariate. Within-study correlation between tests are typically not considered in these approaches. Several DTA network meta-analysis (DTA-NMA) …

Posted in 2021 Volume 20 – Issue 1 Tagged , , , ,

The role of epigenetic factors in descendants from Assisted Reproductive Techniques (ART)

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Vasilios Pergialiotis, Anastasia Prodromidou, Evangelia Dimitroulia, Dimitrios Loutradis

Altogether, Assisted Reproductive Techniques (ART) are likely to cause some epigenetic changes in the offspring, which might consist the molecular basis of complex characteristics and diseases. The present review contributes a large biochemical dataset of a well-defined group of pre- pubertal in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) conceived children in order to detect the potential effect in the offspring’s health …

Posted in 2021 Volume 20 – Issue 1 Tagged , , , , ,

What brings adolescents to the Obstetrics and Gynaecology Emergency Department of a General Hospital

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M. Litos, V. Triantafyllidi, D. Vasileiadou, E. Papamargaritis, C. Sofoudis, K. Bakalianou

Introduction: Paediatric & Adolescent Gynaecology is a special field and also part of the everyday practice. This paper studies the problems adolescent females present with at the Obstetrics & Gynaecology (O&G) Emergency Department (ED). Material and Methods: Data regarding adolescent females that were examined at the O&G ED over one year (2018) were extracted from the records of Konstantiopouleio General Hospital, Athens, Greece …

Posted in 2021 Volume 20 – Issue 1 Tagged , , ,

Luteal phase pregnancy after mirena coil insertion for intrauterine septum resection

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Natasha Louise Citeroni, Rifat Syed

This report is of an unusual case of an intrauterine singleton pregnancy with a Mirena Coil (IUS) in situ following an elective hysteroscopic intrauterine septum resection for treatment of primary subfertility in a 27-year-old female. The patient elected to continue with the pregnancy and underwent additional monitoring via ultrasound. A caesarean section was undertaken at 39-weeks gestation and a healthy male infant was born …

Posted in 2021 Volume 20 – Issue 1 Tagged , , , , ,

A case of bilateral tubal ectopic pregnancy following intrauterine insemination

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Efterpi Tingi, Helena Misiura, Mark Williams, Sunday Ajayi, Srisailesh Vitthala1

The incidence of unilateral ectopic pregnancy (EP) is 1-2% with the tubal EP  being the commonest.  Bilateral tubal pregnancy occurs 1 in every 750 to 1,850 EP following assisted reproductive technologies. We present a case of bilateral tubal EP in a 28 year old woman who underwent intrauterine insemination with donor sperm….

Posted in 2021 Volume 20 – Issue 1 Tagged ,

Second wave of COVID-19 outbreak

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Loutradis Dimitris

The outbreak of the second coronavirus wave resulted in significantly increased number of hospitalizations and accompanying morbidity and mortality outcomes in Greece. Gynecologists face the challenge of juxtaposing the pros and cons of exposing pregnant women to the hospital environment and the potential COVID-19 positive patients. Antenatal screening is rendered challenging in public hospitals and the downside of Greece`s fast response to the first wave of the coronavirus outbreak…